2-hydroxybenzylidene Amino Research Articles

Synthesis, characterization, crystal structure and DFT calculations of dysprosiumIII - (E)-ethyl-4-(2-hydroxybenzylidene amino)benzoate

The luminescent title complex with the formula [Dy(NO3)3L3(H2O)].C2H5OH; C34H38DyN5O17 (L= ethyl (E)-4-((2-hydroxybenzylidene)amino)benzoate) (1) has been prepared and characterized by means of single-crystal X-ray diffraction, FTIR, UV–vis and PL. The Schiff-base ligands are in a zwitterionic form and coordinate through the phenolic oxygen only. The X-ray single-crystal structure of it is described, complex 1 crystallizes in the triclinic space group Pbca. The unit cell parameters are a = 13.7212(5) b = 17.7079(7) c = 31.1562(12) Å, α = 90, β = 90, γ = 90 °, V = 7570.1(5) Å3, Z = 8 completeness = 0.989, Θmax = 24.999, 20,193 reflections collected, 6599 independent reflections, R = 0.0355, wR2 = 0.0705, S = 1.008, parameters = 523, T = 118 K. The capped square antiprismatic arranged dysprosium ion coordination sphere includes three bidentate nitrate groups, two ligands L, that coordinate via their oxygen atoms, and one molecule of water. Furthermore, the chemical structure of complex 1 has been optimized using the PBE-D3BJ/def2-SVP level of theory where ethanol is included as an implicit solvent to mimic the experimental environment. Finally, the complex 1 poses as a potential candidate for light emitting material as it luminous brilliantly in the visible region.

Synthesis, spectral characterization, DNA interaction studies, anthelmintic and antimicrobial activity of transition metal complexes with 3-(2- hydroxybenzylideneamino)-2-methylquinazolin-4(3H)-one and 1,10- phenanthroline

Mixed ligand complexes of cobalt(II) (1), copper(II) (2) and oxovanadium(IV) (3) with 3- (2-hydroxy benzylideneamino)-2-methylquinazolin-4(3H)-one and 1,10-phenanthroline have been synthesized and characterized by elemental analyses, IR, electronic, 1 H-NMR, mass spectra, molar conductance and thermal studies. The synthesized compounds were screened for their in vitro antimicrobial activity. The results show a significant increase in antimicrobial activity of the complexes compared to ligand. Antihelmintic activity of the compounds has been tested on earthworms and the enhanced activity was observed upon complexation. In addition, DNA binding and DNA cleavage studies for the newly prepared compounds were also studied. These studies indicate that the DNA binding and cleavage efficacy were increased in the complexes relative to the parental ligand.