Daily Weight Research Articles

Intermediate- and long-term results after ATOMS (Adjustable Transobturator Male System®) implantation

ObjectivesTo assess outcomes of continence and complications after implantation of Adjustable TransObturator Male System (ATOMS) for the treatment of male stress urinary incontinence (SUI). Materials and MethodsData of 80 patients receiving an ATOMS implatation between 2010 and 2021 at a tertiary academic referral centre were retrospectively analyzed. Primary endpoints were outcomes of continence and complications. Implant survival rate was estimated by the Kaplan-Meier method, risk factors for explantation were analyzed by univariable Cox regression. ResultsDuring a median follow-up of three yrs. the number of pads decreased significantly from four to two pads per day (p<0.001). After five yrs., 17 patients experienced an explantation, eight of them during the first year following ATOMS implantation, resulting in one- and five-year-implant-survival rates of 0.89 (95%CI:0.80-0.95) and 0.71 (95%CI:0.56-0.81), respectively. During the total observation time, ATOMS was explanted in 22 (27.5%) patients (Kaplan-Meier estimate for explantation: 0.35 [95%CI:0.09-0.64]) after a median time of 2.3 (0.1, 10.2) yrs. The risk for explantation was higher in patients after previous incontinence surgery (HR=3.4, 95%CI:1.4-8.2, p=0.007), ISUP (International Society of Urological Pathology) > 4 (Gleason score >8) in surgery specimens (HR=4.4, 95%CI:1.03-27.1 compared to ISUP 1, p=0.046), and a preoperative daily pad weight >250g (HR=3.1, 95%CI:1.18-8.17, p=0.022). ConclusionATOMS lead to a significant reduction of pad usage. During the intermediate-term follow-up approximately every 3rd patient experienced device explantation. In particular, patients with recurrent SUI and patients with severe SUI have to be warned about a relevant risk of explantation.

Combination of Essential Oils and Extracts Enriched with Tocopherols in Diet of Holstein Steers and Its Effect on Ruminal Fermentation, Antioxidant and Anti-Inflammatory Response, Feed Efficiency and Fatty Acid Profile in Meat

Background: This experiment evaluated whether the combination of essential oils (thyme, rosemary, orange) with extracts of Cinnamomum and Quillaja saponaria (enriched with tocopherols) in steers’ diet has positive effects on the health, digestibility, growth, oxidative stress, and fatty acid profile of meat. Methods: The experiment included 24 Holstein steers, divided into two groups, randomly divided (treated = phytogenic mixture (n = 12); control = monensin (n = 12)), undergoing a growth phase of 120 days and 90 days of finishing in individual pens, with a monthly collection of blood, rumen fluid, feces, and feed. Results: In the finishing phase (days 150 to 210), there was a tendency (p = 0.07) toward more significant average daily weight gain when cattle consumed a phytogenic mixture than monensin. The use of the phytogenic product showed greater feed efficiency in the period from 150 to 240 days (p &lt; 0.05), with higher levels of short-chain fatty acids (SCFAs), without differences in the composition of these SCFAs between the control and treated groups, with a reduction in apparent digestibility in the treated group. In blood parameters, the treated group showed higher erythrocyte counts (p &lt; 0.05) without changes in leukocytes, lymphocytes, granulocytes, monocytes, and platelets. The phytogenic treatment demonstrated higher total protein and globulin levels, with increased glucose levels on days 30 and 210 (p &lt; 0.05). Ceruloplasmin and haptoglobin levels increased in the treated group without changes in ferritin, transferrin, C-reactive protein, IgA, and heavy-chain immunoglobulins (p &lt; 0.05). A reduction in oxidative stress was observed using the phytogenic agent, with a marked decrease in the levels of reactive oxygen species (ROS) and carbonyl proteins, with a tendency to increase glutathione S-transferase (p &lt; 0.05). In meat, the phytogenic reduced saturated fatty acids with increased polyunsaturated fatty acids and increased the omega 6/omega 3 ratio. Lower levels of thiobarbituric acid reactive substances and ROS were detected in the meat combined with a higher concentration of total thiols in the treated group than in the control group. Conclusions: The use of the phytogenic in steers’ diets has shown to be a viable candidate for replacing monensin, presenting equal or superior performance results with systemic modulating effects on oxidative stress, meat quality, and serum and biochemical parameters that contribute to more substantial health and efficiency.

Curcuma and Scutellaria baicalensis extracts reduced thermoregulatory behavior in chickens subjected to moderate heat stress

Using phytogenic additives represents a new trend in the poultry feed industry because of purported beneficial impacts. There is limited information about the effects on chicken behavior, but based on new studies, some plant-based active compounds influence animal cognitive function. Therefore, the primary objective of this experiment was to investigate the impact of a feed additive consisting of a mixture of Curcuma and Scutellaria baicalensis on behaviors associated with exposure to heat stress in broiler chickens. Chickens before 21 days of age were kept in 12 littered floor boxes according to guidelines for Cobb 500 hybrid. The Cobb 500 chickens of both sexes were fed identical diets until they reached 21 days of age. From this point onward, the experimental group received in the diet a 0.1% supplement containing Curcuma and Scutellaria baicalensis extracts. The control group received a feed mixture without phytogenic additives. Both groups had six replicates, and each group comprised 75 chickens. The pens of experimental and control group were randomly selected. The experimental period spanned from 28 to 35 days of age, during which the chickens were subjected to mild constant heat stress (28°C). Ethological observations were conducted at 31, 32, and 33 days of age, divided into three observation periods at the beginning, middle, and end of the daylight period (18h) using the visual scan sampling method. After the experimental period at 35 days of age, chickens from both groups exhibited nearly identical live body weights and daily feed intake. However, the experimental group demonstrated significantly higher daily weight gain (P < 0.05). Thermoregulatory behaviors such as panting and wing spreading were suppressed (P < 0.05) in the experimental group, while there was a simultaneous increase in the number of chickens that were feeding (P < 0.05). Similarly, age significantly influenced behavioral patterns (P < 0.05), whereas time of the day only affected the number of chickens engaged in feeding (P < 0.05). In conclusion, the feed mixture enriched with Curcuma and Scutellaria baicalensis extracts exhibited performance-enhancing and behavior-changing effects, providing significant insights into the potential of this feed additive in improving performance and reducing thermoregulatory behavior manifestations within a flock under heat-stress conditions, thereby informing the poultry feed industry of a promising new development.

Effects of mistletoe leaf (Viscum album) aqueous extracts on performance, hematology and serum biochemistry of rabbits in a humid tropical environment

The study examined the physiological effects of mistletoe leaves Aqueous Extracts (MLAE) on the performance, haematology and some serum biochemistry of rabbits. Thirty New Zealand white x Chinchilla weaned rabbits of 28days old were matched for weight, sex and randomly assigned to five groups (n=6 per-group), sub-divided into two replicates of three rabbits each. The basal diet was forages Tridax procumbens and Ipomea batata leaves 20 g morning and evening daily as common rabbit feed available in the environment. The rabbits were served twice daily with mistletoe leaves aqueous extracts 200mls of 20g dried leaves from four host trees and water 200 ml twice daily as control. All rabbits were fed ad libitum throughout the ten weeks period of the study. The proximate results revealed that mistletoe leaves from the four host trees were rich in crude protein, crude fibre and ash, which provided protein and minerals supplement for rabbits’ performance. Data obtained were subjected to one-way ANOVA and significant means separated using Turkey’s Comparision Test. Results on performances showed significant(P&lt;0.05) difference between treatments indicated with the following ranges: final body weight (1220.00–1490.00g), daily weight gain (9.86-11.40g/d). Feed conversion ratio (0.11-0.86), total feed intake (4122.00–4392.00), total water and mistletoe aqueous extracts (8974.00-11627.00mls), Heamatology and serum biochemistry analysis results revealed significant p&lt;0.05) difference between treatments compared to the control. The differences between the treatments could be attributed to mistletoe and their host trees, since mistletoe are hemi-parasites, depend partly on their host for nourishment. Extracts yielded good rabbit performance and blood physiological response, hence it could be used for forage–concentrate feed supplement for rabbits during dry season scarcity of forages.

Genetic parameter estimation of preweaning growth traits in Akkaraman sheep.

This study aimed to evaluate (co)variance components and heritability of pre-weaning body weight traits and the Kleiber ratio in Akkaraman sheep. Data collected between 2018 and 2023 from Çankırı province, Türkiye, formed the basis of this research. The considered traits were birth weight (BW), weaning weight (WW), average pre-weaning daily weight gain (ADWG), and Kleiber ratio (KR). Utilizing animal mixed models and the average information restricted maximum likelihood (AI-REML) procedure, genetic parameters were estimated. Direct heritability estimates were 0.30 ± 0.02, 0.23 ± 0.02, 0.23 ± 0.02, and 0.28 ± 0.03 for BW, WW, ADWG, and KR, respectively. Maternal genetic heritabilities were 0.03 for WW and 0.02 for WW, ADWG, and KR. Direct genetic correlations among pre-weaning growth traits were negative for BW-WW and BW-ADWG and positive for WW-ADWG at -0.05, -0.23, and 0.98, respectively. The moderate direct heritability estimate suggests the presence of genetic variability in the Akkaraman sheep breed, indicating potential genetic progress through selective breeding. Despite the low maternal permanent environmental effects, the significant impact of maternal care on lamb growth in this breed underscores the importance of considering both direct and maternal effects in the genetic evaluation of early growth traits. The observed negative genetic correlations among birth weight, weaning weight, and daily live weight gain until weaning emphasize the need for careful consideration in selection programs for the Akkaraman breed.

The growing, resilient, inclusive and sustainable (GRINS) project for the development of life cycle inventory databases of beef cattle raised in Italy: The statistical datasets and the environmental assessment

Within the framework of the Growing, Resilient, Inclusive and Sustainable (GRINS) project (Spoke 1, WP3, Next Generation EU program), this work aims to overcome the absence of Italian beef cattle Life Cycle Inventory (LCI) datasets through a capillary analysis of several parameters. Specifically, the contribution to the environmental impact of livestock breeding of breed features (age, gender, weight, daily weight gain, breeding, feed intake and composition, milk and manure production), as well as stable management and crop cultivation was investigated. Statistical inventory datasets (84 in total) were developed for the predominant (<1 % population cut-off) beef cattle breeds in Italy.A key finding was the quantification of CH4 emissions from enteric fermentation (ranging from0.259 to 0.714 g kg−1 of live weight per day) and its contribution to the overall environmental impact of beef cattle breeding. The composition of feed rations emerged as critical, influencing both cattle emissions and environmental impacts associated with the cultivation and transport of raw materials. Intensive and langer breeds like Aubrac, Blond d'Aquitaine, Blue Belga, Charolaise, and Chianina, exhibited higher eco-indicator values compared to the extensive beef cattle breeds (Podolica, Highland, and Maremmana). The life cycle assessment identified several key impact categories (climate change, water use and ecotoxicity freshwater) mainly contributing to the total eco-indicator. Climate change (22.1 %) represented the greatest impact category, with beef cattle emissions over their lifespan averaging 9.3 Mg CO2-eq. Methane (enteric fermentation) and NH3 (manure management) emissions, as well as irrigation and pesticide use, represented the main hotspots. A comparative analysis evaluated the environmental footprint of Italian beef cattle against benchmarks outlined in the “Made Green in Italy” brand's Product Category Rules. This comparison revealed a 32.4 % reduction in total eco-indicator for Italian beef cattle, due to a significant decrease in freshwater ecotoxicity (−72.5 %), land use (−34.2) and climate change (−7.5 %).

Functional Characterization and Toxicological Study of Cordyceps militaris in Weaned Pigs

Cordyceps militaris (CM), a well-known parasitic fungus that grows on the larvae of Lepidoptera, has a variety of pharmacological activities. However, little is known about its safe dosage for animals, including pigs. To explore its effect on intestinal health and evaluate its safe dosage, 30 weaned pigs were randomly allotted to five groups and fed with a basal diet supplemented with different doses of CM for 42 days. The results showed that CM supplementation at 100 mg/kg increased the average daily weight gain (ADG) and significantly decreased the ratio of feed intake to gain (F:G) in the weaned pigs (p &lt; 0.05). However, CM supplementation at a higher dose (1000 to 4000 mg/kg) had no effect on growth performance. CM supplementation at 100 mg/kg also increased the digestibility of gross energy and increased the ratio of villus height to crypt depth (V/C) in the duodenum and ileum (p &lt; 0.05). Moreover, CM supplementation at 100 mg/kg increased the activities of catalase (CAT) and total antioxidant capacity (T-AOC), but decreased the concentration of malondialdehyde (MDA) in serum (p &lt; 0.05). Importantly, histopathological studies of tissues (e.g., heart, liver, kidney, spleen, lungs, pancreas, thymus, mesenteric lymph nodes, stomach, and small intestine), organ indexes, major hematological parameters, and serum biochemical parameters were not affected upon CM supplementation. These results suggest that CM may have the potential to act as a safe and effective supplement to improve the growth performance and intestinal health of weaned pigs.

Assessment of feeding hydroponic fodder on growth and reproduction performance in Black Bengal goat.

This study aimed to evaluate the effects of hydroponic fodder on the growth and reproductive performance of Black Bengal goats in East Champaran, Bihar, during the years 2020-21 and 2021-22. A total of 24 goats were randomly assigned to four groups: Control (C) with extensive grazing, gram straw, concentrate feed, and green fodder; Treatment 1 (T1) receiving C + 300g/day of wheat hydroponic fodder; Treatment 2 (T2) with 300g/day of maize hydroponic fodder alone; and Treatment 3 (T3) receiving C + a combination of 150g/day of wheat and 150g/day of maize hydroponic fodder. Each group comprised 6 animals. The nutrient composition analysis revealed that wheat hydroponic fodder had significantly higher (P < 0.05) levels of dry matter, crude protein, and lignin, whereas maize contained higher nitrogen-free extract, crude fiber, ether extract, and ash. In terms of growth performance, T3 showed the highest body weight gain and daily weight gain, outperforming T2, T1, and the control group (P < 0.05). Though differences between T2 and T3 were not significant (P > 0.05) across both years, T3 consistently exhibited better performance. Reproductive performance indicators, such as age at puberty, age of first kidding, and kid mortality rates, were significantly lower (P < 0.05) in T3, T1, and the control group compared to T2. However, there were no significant differences (P > 0.05) between T2 and T3 in these parameters. T3 also showed the highest kidding size and birth weight of kids (P < 0.05), followed by T2, T1, and the control group. The cost of feed per kilogram of body weight gain was lowest in T3, followed by T2, T1, and the control. In conclusion, the combination of maize and wheat hydroponic fodder (T3) resulted in better growth and reproductive performance compared to feeding maize or wheat hydroponic fodder alone. Furthermore, this feeding strategy reduced the cost per kilogram of live weight gain, indicating its potential for enhancing the sustainability and profitability of goat farming systems in the region.

Evaluation of biofloc system effects on water quality, growth, innate immunity, physiological status, and immune- and growth-related gene expressions in early growth stages of thin-lipped mullet (Liza ramada)

AbstractA 90-day experiment was carried out to study the influence of biofloc system on water quality, growth, feed utilization, survivability, bacteria in fish gut, and physiological and immunological responses of thin-lipped mullet (Liza ramada). Two treatments, clear water (CW) and biofloc (BFS), were each designed in triplicates. Both treatments were stocked with Liza ramada (mean weight of 1.18 ± 0.02 g). BFS group showed the highest final body weight, weight gain, average daily weight gain, and specific growth rate, the lowest feed conversion ratio, and the highest protein efficiency ratio and survivability. The proximate analysis of biofloc samples showed that percent crude protein and lipid were 26.17 and 7.75% respectively with the presence of essential minerals required for fish growth. The total body chemical composition of fish demonstrated improved crude protein and fat in Liza ramada stocked in BFS compared to CW. The highest total bacterial count and Bacillus number were recorded in the intestine of fish kept under BFS. Protease, lipase, and amylase levels significantly increased in fish stocked in BFS. The highest antioxidant activity was observed in fish kept under BFS treatment, while cortisol, alanine aminotransferase, and serum aspartate aminotransferase showed the lowest activity. Significantly high serum total protein, serum albumin, serum globulin, phagocytic activity, lysozymes, respiratory burst activity, and immunoglobulin M were observed in fish raised in BFS compared to CW. The intestinal histomorphometry examination showed a significantly high villi length and width, crypt depth, high number of intraepithelial lymphocytes, and goblet cells in BFS group. BFS resulted in a significantly up-regulation of the immune genes in the liver (IL-1β, TNF-α, IL-8, and IL-10) and the growth-related genes in the liver (IGF-1 and GH) compared to CW treatment. These results revealed that applying biofloc system in the rearing of Liza ramada resulted in many advantages including growth improvement, high survivability, enhanced activity of digestive enzymes, antioxidant system, immunological response, gut health, and decreased stress enzymes.

Optimization of solid-state fermented corn distillers dried grains with solubles: effects on growth performance and tissue morphology in broiler chickens

In recent years, the use of corn DDGS has alleviated the problem of protein feed shortages to a certain extent; however, its high mycotoxin content seriously restricts its application in feedstuffs. In this study, the conditions of solid-state fermented corn DDGS were optimized to investigate changes in the nutrient composition of solid-state fermented corn DDGS and their effects on the growth performance and histological section of yellow-feathered broilers. The optimal strain ratio for solid-state fermentation was determined by orthogonal testing as 1:1:2 for B. desmois JA3:B. subtilis ANSB01G: and B. subtilis ANSB060, and the response value was the score of the degradation rate of Deoxynivalenol (DON), zearalenone (ZEN), and aflatoxin B1 (AFB1) weighted by 4:4:2. Optimal conditions for the solid-state fermentation of maize DDGS were determined by B-Behnken response surface design: the inoculum amount was 1%, the feed to liquid ratio was 1:1.25, the fermentation temperature was 37°C, and the fermentation time was 29.5 h. The optimal conditions for solid-state fermentation of maize DDGS were as follows: the inoculum amount was 1%, the material-liquid ratio was 1:1.25, the fermentation temperature was 37°C, the fermentation time was 29.5h, and the degradation rates of DON, ZEN, and AFB1 in the fermented maize DDGS were 81.6%, 55.18%, and 41.14%, respectively. Moreover, solid-state fermentation significantly improved the nutrient content, in which the amounts of amino acids, crude ash, and crude fat were significantly increased (P &amp;lt; 0.05) and the content of crude fiber was significantly decreased (P &amp;lt; 0.05). The in vitro digestibility of dry matter, crude protein and crude fiber increased significantly (P &amp;lt; 0.05); in addition, compared with the control group, the addition of fermented maize DDGS significantly increased the daily calorific intake of broiler chickens, the daily weight gain (P &amp;lt; 0.05); heart, liver and intestinal tissues underwent no obvious pathological changes.

Evaluation of the Chemical Composition and Feeding Value of Sweet Orange Pulp and Pineapple Peel Meals as Fibre Sources in Pigs’ Rations

The piggery industry in Nigeria is on the verge of collapsing due to the high cost of conventional feed resources including wheat offal and palm kernel cake that usually form bulk in the diets of pigs. This study was, therefore, designed to compare the chemical composition of orange pulp meal, pineapple peel meal, and wheat offal and evaluate their feeding value in pig rations. The orange pulp and pineapple peels were dried on a concrete floor and analyzed for chemical composition. Three experimental diets were formulated with orange pulp and pineapple peel meals replacing wheat offal as a fibre source. Thirty crossbred (Chester white x Landrace) growing pigs with an average initial weight of 8.20 -- 8.75kg were distributed into three groups, with ten animals per group, and assigned to the three experimental diets. The average daily feed intake and weight gain were monitored throughout the 56-day duration of the experiment. Seven days to the end of the experiment, three pigs randomly selected for the digestibility trial were individually housed in metabolism crates and allowed 5 days of adaptation to the crates and feed before faecal collection commenced. Animals were fed the experimental diets at approximately 4% of their body weight, and the faeces of the animals were collected for 5 days. The determination of the nutrient composition of feed and faecal samples was performed. Data collected were subjected to analysis of variance using a completely randomized design. The result indicated that samples were significantly (P&lt;0.05) different in crude protein composition, with the wheat offal having the highest value corresponding to 9.21 ± 0.12%. Orange pulp had the highest content of ash (6.72 ± 0.12%). The gross energy values were 15.23MJ/kg, 15.31MJ/kg and 16.15MJ/kg for pineapple peel, orange pulp and wheat offal, respectively. The highest manganese concentration was observed in wheat offal (5.19± 0.11mg/l), while orange pulp and wheat offal were higher in sodium and phosphorus concentrations. The pigs fed an orange pulp meal diet recorded the highest average daily weight gain (0.31 kg) and a superior feed conversion ratio (4.19) relative to others. Digestibility values were similar across the three treatment groups. It was, therefore, concluded that orange pulp and pineapple peal meal could serve as alternative fibre sources in growing pigs' rations. Key words: Wheat offal, pineapple peel, orange pulp, growing pigs, digestibility

Rearing of black soldier fly (Hermetia illucens) larvae as a tool for managing agricultural byproducts

The aim of this study was to evaluate the effects of cassava, yam and sweet potato peels on Black Soldier Fly Larvae (BSFL) production. Four different treatments were performed in triplicate in a completely random block consisting of soy bran (TSB), cassava peel (TCP), yam peel (TYP) and sweet potato peel (TPP). A density of 1 larva/g of substrate was used with a uniform ratio of 100 mg/larva/day. Larval growth duration was ten days, and growth monitoring was carried out every 2 days. The daily weight gain (DWG) ranged from 2.19 ± 0.09 g/day (TYP) to 4.53 ± 0.02 g/day (TSB). The production of these BSFL ranged from 43.90 ± 1.87 g/kg of substrate (TYP) to 90.56 ± 0.54 g/kg of substrate (TSB). The degradation rate ranged from 36.00 ± 2.30% (TYP) to 65.00 ± 2.88% (TSB), and the survival rate ranged from 77.66 ± 1.45% (TYP) to 99.00 ± 0.28% (TSB). According to the Z correlation test, there was a strong correlation between the organic matter content of the substrates and the DWG (99.1%). It was also observed that phosphorus content was strongly correlated with DWG (92.9%). Regarding the nutritional quality of the larvae, the protein content varied from 33.51 ± 0.94% (TYP) to 40.64 ± 032% (TSB), and the lipid content varied from 26.24 ± 0.35% (TYP) to 30.44 ± 0.18% (TSB). A significant difference (p < 0.05) between the different treatments depending on the parameters were noticed. This study revealed that cassava, yam and sweet potato peels can be used for BSFL production, but the best growth of BSFL was obtained with the cassava peel substrate that presented also the best degradation rate.

Application of PID algorithm in temperature control of pig houses farmers' mental health from the perspective of social ecological system and its implications for agricultural production efficiency

This study investigates the application of PID algorithm-based temperature control systems in pig house environmental management and its impact on agricultural production efficiency. Through field experiments conducted at Dongshun Aquaculture Ecological Development Co., Ltd. in Nanping City, Fujian Province, we evaluated the system's effectiveness in energy efficiency, production performance, and animal health. Results show that the PID system achieved 18.5% energy savings, a 9% increase in daily weight gain, and a 7.1% improvement in feed conversion ratio. Additionally, meat quality scores improved by 8.3%, and disease incidence rates decreased by 21.9%. Economic analysis indicates that the system begins to generate a positive return on investment in the second year, with cumulative benefits reaching 192% within five years. These findings highlight the potential of PID temperature control systems in improving pork production efficiency and sustainability, offering a valuable solution for modern pig farming.

Effect of dietary supplementation of yeast culture Saccharomyces cerevisiae in lactating female goats.

This study was designed to investigate the effects of adding a novel yeast culture, Saccharomyces cerevisiae refermented sorghum distiller's dried grains with solubles (SSDDGS), to the diets of lactating female goats on lactation performance and lamb growth performance. We divided 10 lactating Dazu black goats of similar age, weight, and offspring into two groups: one fed a pelleted diet with 50 g/day SSDDGS (ET), and the other without SSDDGS as a control (EC) for 7 weeks. We monitor the weight changes of each goat and collect blood and milk samples from experimental ewes at specific times for hormone and milk composition determination. We use ultra-performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) to detect metabolites in the serum of lactating ewes. Our results showed that SSDDGS supplementation significantly reduced female goats' average daily weight loss during weeks 2-4 of lactation and increased serum IGF-1 and prolactin levels at week 4 (p < 0.05). SSDDGS supplementation in early lactation significantly increased milk protein, lactose, and ash content (p < 0.05). UPLC-MS/MS analysis showed that SSDDGS changed the levels of 58 metabolites in the serum of lactating goats. These metabolites were mainly involved in the sohingolipid signaling pathway, and cysteine, methionine, and sphingolipid metabolism. In summary, Yeast culture SSDDGS reduced weight loss, enhanced milk quality, and modified metabolic profiles in early lactation goats, providing insight into the potential regulatory role and mechanism of yeast culture in lactation female goats.

Anatomical and carcass traits, partition of fat deposits, and meat quality in culled adult goats finished with high-fat diet

The objective of this study was to examine the impact of a high-fat finishing diet on the in vivo performance, anatomical and carcass characteristics, and meat quality of adult culled goats. Over a period of 28 days leading up to slaughter, eighteen adult culled goats were subjected to a finishing diet provided in quantities sufficient to meet 3.0 times the nutritional requirements of adult non-dairy maintenance goats. The female goats were divided into two groups: one fed with the baseline diet without fat supplementation (n = 9) and the other fed a diet concentrated supplemented with whole full-fat linseed (n = 9). The diets varied in fat content (2.8% vs. 8.4% DM). The high-fat group exhibited a higher dry matter intake compared to the control group (+37%), along with elevated plasma cholesterol and triglyceride levels. The control group experienced a significant decrease in daily weight gain between the second and final week of the finishing period (-70%), in contrast to the increase observed in the high-fat group (+59%). At slaughter, no differences were noted between the groups in anatomical and carcass characteristics. Additionally, no differences were found between the diets regarding proximate composition, pH, yellow color component, and lightness of loin. The high-fat group exhibited a higher redness of loin. The inclusion of high-fat levels in finishing diets for culled adult goats allows for increased feed intake and performance but does not appear to affect carcass or meat quality.

Comparative Effect of Feeding Maiwa and Pearl Millet as Dietary Energy Source for Broiler Chicken

This study compared the effects of feeding broiler chickens, maiwa and pearl millet as dietary energy sources. The effectiveness, performance, and carcass features of broiler chickens given varying amounts of maiwa and pearl millet as dietary energy sources were evaluated in a feeding trial/experiment. The experiment used 200 day-old broiler chickens. The experiment was divided into two phases: starter and finisher. Five experimental meals containing 20 and 23% crude proteins were created for each phase. For T1, T2, T3, T4, and T5, five experimental diets were developed with different inclusion levels of 0, 25, 50, 75, and 100% respectively. In a randomized completely block design (RCBD), each treatment was duplicated four times, with ten birds each replication. Feed and water were provided ad libitum from 2nd to the 9th week of age. The result of the experiment on percentage composition of the experimental diets indicated that crude protein and metabolizable energy are within the range adequate for raising broiler chickens. The daily feed intake values (53.80-57.05g; 120.30-124.35g; 82.79-85.35g) and the daily weight gain values (29.95-33.82g; 41.77-44.66g; 34.22-35.88g) obtained from the performance of broiler chickens revealed non-significant differences among the treatments in the three (3) phases. The dietary treatments had no effect on the carcass and visceral organ parameters of broiler chickens, with the exception of caecal weight and small intestine length, which differed significantly (P≤0.01), with values ranging from 0.41%-0.72% and 160.85-191.33cm, respectively. Thus, the study comes to the conclusion that broiler chickens can safely be fed maiwa and pearl millet along with other items as nutritional energy sources.

Modification of Intestinal Flora Can Improve Host Metabolism and Alleviate the Damage Caused by Chronic Hypoxia.

Prolonged exposure to hypoxic conditions can lead to reduced appetite, stunted growth, systemic inflammation, and pulmonary hypertension. Previous studies have indicated a correlation between gut dysbiosis and the development of hypoxia-related hazards. We designed an experiment to investigate the effect of microbiota on mitigating hypoxic damage. Gut microbiota from high-altitude-adapted species (Ochotona curzoniae) were transplanted into Sprague Dawley (SD) rats, which were then housed in a simulated 6000 m altitude environment for 30 days. After the experiment, we conducted analyses on average daily weight gain (ADG), feed conversion ratio (FCR), mean pulmonary artery pressure (mPAP), gut flora, and fecal metabolism. The results demonstrated that the ADG in the transplantation group (2.98 ± 0.17 g) was significantly higher than in the control groups (2.68 ± 0.19 g and 2.26 ± 0.13 g) (p < 0.05). The FCR was reduced in the transplantation group (6.30 ± 0.33 g) compared to the control groups (8.20 ± 1.15 g and 8.83 ± 0.45 g) (p < 0.05). The mPAP was decreased in the transplantation group (38.1 ± 1.13 mmHg) compared to the control groups (43.4 ± 1.30 mmHg and 43.5 ± 1.22 mmHg) (p < 0.05). Multi-omics analysis revealed that Lachnospiraceae, Desulfovibrionaceae, and specific amino acid metabolic pathways play crucial roles in hypoxia and are associated with both inflammation and nutritional metabolism. This study proposes a novel approach to the treatment of hypoxic pulmonary hypertension and holds potential significance for improving high-altitude developmental potential.

VARIASI PAKAN DALAM MENDUKUNG PRODUKTIVITAS SAPI ACEH DAN SAPI BALI DI INDONESIA

The survival of Acehnese and Balinese cattle is affected by feed that contains nutrients to support the growth and productivity of livestock. Feed quality, quantity and continuity are problems that affect the productivity of local cattle in Indonesia. The most commonly used forages in feeding Aceh and Bali cattle are elephant grass dan field grass, while the most commonly used concentrates are palm fronds and corn. A combination of 80% forage and 20% concentrate tends to be better for increasing daily weight gain of Aceh and Bali cattle.

Vitamin D3 requirements and relative bioavailability for starter male White Pekin ducks fed either cholecalciferol or 25-hydroxycholecalciferol

The objectives were to investigate effects of various concentrations of dietary vitamin D3 (VD3) or 25-hydroxycholecalciferol (25-OH-D3) on growth performance, VD3 status, calcium (Ca) metabolism, and tibia mineralization of starter male White Pekin ducks, and dietary requirements and relative bioavailability of these two compounds. One-day-old male White Pekin ducks (n = 624) were assigned to 13 dietary treatments, including 6 added VD3 concentrations (100, 200, 400, 800, 1200, and 2000 IU/kg), and 2 vitamin D3 sources (VD3 and 25-OH-D3), plus a negative control (no vitamin D3 supplementation) for 21 days. Each group had 6 replicate pens of 8 birds per pen. At 21 days of age, growth performance, carcass traits, plasma 25-OH-D3 and Ca content, and tibia mineralization were examined. There was a high incidence of leg disease and mortality in ducks fed the control diet; however, those negative effects were avoided by adequate VD3 or 25-OH-D3 supplementation. Ducks in the negative control group had the lowest body weight, average daily weight gain (ADG), average daily feed intake (ADFI), breast muscle percentage, plasma 25-OH-D3, plasma Ca, and tibia indices (weight, diameter, ash, density, tibia mineral, strength) (P < 0.05), with all these end points enhanced linearly or quadratically as dietary VD3 or 25-OH-D3 increased (P < 0.05). Furthermore, at 100 or 200 IU/kg, ducks fed 25-OH-D3 had greater body weight, ADG, ADFI, plasma Ca, plasma 25-OH-D3, tibia weight, tibia diameter, tibia ash than those fed VD3 (P < 0.05), indicating 25-OH-D3 was more effective in stimulating growth, Ca absorption, and tibia mineralization. For growth performance, breast muscle percentage, plasma Ca, and tibial indices of starter male Pekin ducks, the VD3 requirements were 281 to 633 IU/kg, whereas 25-OH-D3 requirements were 119 to 395 IU/kg. Based on slope ratio comparisons from multiple linear regressions of plasma 25-OH-D3, bioavailability of 25-OH-D3 was 186% relative to cholecalciferol.

Effect of Melatonin on the Production Performance, Blood Biochemical Parameters, Nutrient Digestibility, and Gastrointestinal Microbiome of Liaoning Cashmere Goats

Melatonin’s capacity to improve cashmere production and quality in goats is well established, but its underlying mechanisms, particularly those concerning the gastrointestinal microbiome, remain inadequately understood. This study aims to elucidate the effects of melatonin implantation on the production performance, blood biochemical parameters, nutrient digestibility, and gastrointestinal microbiome of Liaoning cashmere goats. Thirty newborn Liaoning cashmere goat lambs were selected and randomly assigned to control and melatonin groups using a paired test design. The melatonin group received three melatonin implantations at 15, 75, and 135 days of age, respectively, with a dosage of 2 mg/kg body weight, while the control group received no treatment. Digestive metabolism tests were conducted at 150 and 300 days of age; prior to these tests, blood, rumen fluid, and rectal feces were collected. Apparent nutrient digestibility and blood biochemical indexes were determined, and rumen fluid and rectal feces were analyzed using microbial 16S rRNA sequencing. The results indicated that melatonin significantly reduced daily weight gain and body weight at 60 days (p &lt; 0.05) while significantly increasing daily weight gain at 300 days (p &lt; 0.05). Additionally, it significantly increased cashmere length and reduced its fineness (p &lt; 0.05). Melatonin significantly enhanced nitrogen deposition (p &lt; 0.05), elevated plasma levels of T-AOC, CAT, GSH-PX, and BUN (p &lt; 0.05), and reduced plasma levels of MDA, GOT, GPT, and AKP (p &lt; 0.05). Moreover, melatonin significantly elevated the microbial Ace and Chao1 indices in rectal feces (p &lt; 0.05), increasing genera beneficial for feed digestion and absorption, including Prevotella, Lachnospiraceae, Ruminococcus, and Synergistaceae (p &lt; 0.05); the abundance of these beneficial genera were positively correlated with improved cashmere production performance, antioxidant activity, and liver and kidney function. In conclusion, melatonin enhances cashmere production by modulating gastrointestinal microbiota, antioxidant activity, liver and kidney function, and nitrogen metabolism in cashmere goats. This study provides a theoretical foundation for melatonin’s role in microbiota modulation, which is essential for promoting high-quality and sustainable development in the cashmere goat industry.