α-Fe2O3 Particles Research Articles

Novel hollow α-Fe2O3 nanofibers with robust performance enabled multi-functional applications

The synthetic strategies of achieving low-cost and high-performance nanofibers are of great significance in the field of catalysis and detection. In this work, a series of electrospun α-Fe2O3 nanofibers with hollow structure were prepared via combination technology of electrospinning, hydrothermal synthesis, and controlled calcination process. Especially, the influences of the crystal structure and morphology on the comprehensive properties of nanofibers have been explored in detail. The results indicated that α-Fe2O3 nanofibers could be obtained via the calcination at 600–800 °C. Rice-like α-Fe2O3 particles were observed to assemble a stable exoskeleton, supporting a robust tubular cavity. And this tubular structure turned gradually into groove-like structure as the calcination temperature increased, accompanied by tunable crystallization, specific surface area and magnetic property. Finally, combined with series of validation tests, including dye decolorization, electrochemical detection of trace cadmium ions and Fenton degradation of polyvinyl alcohol, the resultant α-Fe2O3 nanofibers have been demonstrated to show the potential application prospects.

Tunable Synthesis of Hematite Structures with Nanoscale Subunits for the Heterogeneous Photo-Fenton Degradation of Azo Dyes

Facile syntheses of branched hematite (α-Fe2O3) crystals with fine-tuning of their nanoscale subunit morphologies were reported. Starting from Prussian red and bisolvent systems with controlled temperature as the crucial parameters, fine-tuning of the nanoscale subunit morphologies in the context of controlling the anisotropic growth of branched α-Fe2O3 crystals was demonstrated. The systematic and optimized studies significantly improved the controlled synthesis of the hierarchical growth of nanoscale subunits, leading to the formation of branched dendritic leaflike (secD3D, tertD2D, and tertD3D) and hyperbranched (secS2D and hypB2D) α-Fe2O3 particles for their size-reduced variants used in photocatalysis. The kinetics of the photo-Fenton degradation of three azo dyes (chlorazol black, direct blue, and methyl orange) with five types of branched dendritic α-Fe2O3 particles were compared systematically.

Enhanced Photo-Fenton Activity of SnO2/α-Fe2O3 Composites Prepared by a Two-Step Solvothermal Method

The x-SnO2/α-Fe2O3 (x = 0.04, 0.07, and 0.1) heterogeneous composites were successfully prepared via a two-step solvothermal method. These composites were systematically characterized by the X-ray diffraction technique, field emission scanning electron microscopy, an energy dispersive spectrometer, X-ray photoelectron spectroscopy and a UV–visible spectrometer. It was found that SnO2 nanoparticles were uniformly decorated on the surface of α-Fe2O3 particles in these heterogeneous composites. A comparative study of methylene blue (MB) photodegradation by α-Fe2O3 and x-SnO2/α-Fe2O3 composites was carried out. All x-SnO2/α-Fe2O3 composites showed higher MB photodegradation efficiency than α-Fe2O3. When x = 0.07, the MB photodegradation efficiency can reach 97% in 60 min. Meanwhile, the first-order kinetic studies demonstrated that the optimal rate constant of 0.07-SnO2/α-Fe2O3 composite was 0.0537 min−1, while that of pure α-Fe2O3 was only 0.0191 min−1. The catalytic mechanism of MB photodegradation by SnO2/α-Fe2O3 was examined. The SnO2 can act as a sink and help the effective transfer of photo-generated electrons for decomposing hydrogen peroxide (H2O2) into active radicals. This work can provide a new insight into the catalytic mechanism of the photo-Fenton process.

Effect of microstructure on complex permittivity and microwave absorption properties of recycled α-Fe2O3 nanopowder prepared by high-energy ball milling technique

This study was aimed at investigating the effect of microstructural variations on relative complex permittivity and microwave absorption properties of recycled α-Fe2O3, following application of high-energy ball milling technique to modify particles into nanopowder. Three portions of recycled α-Fe2O3 granules were separately milled for 8 h, 10 h and 12 h respectively and their microstructural characteristics were examined using X-ray diffraction (XRD), High-resolution transmission electron microscopy (HRTEM) and Brunauer-Emmett-Teller (BET) analysis. This was followed by relative complex permittivity and microwave absorption characterizations which were conducted at X-band microwave frequency range using the rectangular waveguide technique in connection with a vector network analyzer. Results established interfacial lattice defects and imperfections in the milled portions which became more pronounced with reduced crystallite sizes, and contributed to enhanced interfacial polarization process, leading to increased relative complex permittivity and microwave absorption properties of the recycled α-Fe2O3 nanopowders. The smallest estimated crystallite size of 11.1 nm was obtained after 12 h of milling with ɛr = 12.1–0.46j at 8 GHz, which was reduced to ɛr = 11.0–0.34j at 12 GHz while its power loss values varied between 18.3 dB and 23.3 dB in the 8–12 GHz range. A positive correlation was identified that connects microstructural variations with relative complex permittivity and power loss, and could be exploited to tune the microwave absorption properties of the recycled α-Fe2O3 particles.

One-step solution auto-combustion process for the rapid synthesis of crystalline phase iron oxide nanoparticles with improved magnetic and photocatalytic properties

We report the solution auto-combustion (AC) process for the rapid synthesis of Fe3O4 nanoparticles derived from the sol–gel (SG) process. The citric acid (CA) and tartaric acid (TA) is used as gelling agents in the SG process, where the citric acid turns into a fuel that combusts the gel and yields a highly magnetic crystalline phase Fe3O4 nanoparticles in one step with an average particle size of 50 nm. In contrast, the citric acid at different concentrations and tartaric acid at any concentrations do not lead to any combustion process and yield amorphous iron oxides. Upon annealing, these CA and TA derived iron oxide samples are turned to crystalline phase α-Fe2O3 particles. In contrast, the as-synthesized AC sample (i.e. Fe3O4) is oxidized to γ-Fe2O3 phase, which is confirmed from their respective XRD, Rietveld refinement and XPS studies. All the synthesized iron oxide phases showed broad visible light absorption. The room temperature M−H hysteresis curves obtained from VSM revealed that the Fe3O4 and α-Fe2O3/γ-Fe2O3 phases exhibit super-paramagnetic and ferromagnetic properties, respectively. The photocatalytic efficiencies of the samples are found to be in the order of Fe3O4 > γ-Fe2O3 > α-Fe2O3 with 98, 87, 79/73% degradation of rhodamine B dye at the end of 3 h and H2 evolution rate over these systems is found to be 2.1, 1.3 and 0.92/0.89 mmol/h/g, respectively under simulated solar light irradiation. The photocatalytic recycle studies demonstrated that all the synthesized photocatalysts possess excellent chemical and photo-stabilities.

Hematite photoanodes prepared by particle transfer for photoelectrochemical water splitting

α-Fe2O3 particles were prepared by a solution-derived method with annealing at ∼800 °C. By particle transfer, the particles were applied to photoanodes for photoelectrochemical water splitting.

Fabrication of Pd-loaded α-Fe2O3 decorated rGO hybrids for highly sensitive H2 sensing

Pd-loaded α-Fe2O3 particles decorated on reduced graphene oxide (rGO) hybrids have been successfully synthesized via hydrothermal. This simple strategy can be expected to provide the conditions for the manufacture of similar metal oxide mixtures using different precursors. The morphological and structural characteristics of the product were investigated by scanning electron microscopy (SEM), X-ray diffraction (XRD), and X-ray photoelectron spectrometry (XPS). Utilized as the composite materials in sensors, the sensor based on Pd(0.5%)-Fe2O3/rGO demonstrated an excellent selectivity towards H2 at 180 °C in various gases, with a highly sensitive response of 78.4% along with a fast response and recovery (19 s, 6 s) to 1000 ppm H2. The combination of α-Fe2O3 particles decorated on rGO and catalytic activity of Pd0-loaded present a very charming sensing behavior for applications as real-time monitoring gas sensors.

Response to Comment on Oil-Dispersed α-Fe2O3 Nanoparticles as a Catalyst for Improving Heavy Oil Oxidation

The main goal of our previous work was to study the effect of coating the hematite (α-Fe2O3) particles with oleic acid on their catalytic properties for improving heavy oil oxidation (https://doi.org/10.1021/acs.energyfuels.1c00657). We concluded that “Compared with α-Fe2O3, α-Fe2O3@OA more efficiently catalyzed the combustion of heavy oil due to its good dispersion in heavy oil. α-Fe2O3 was found to be transformed into smaller size magnetite (Fe3O4), maghemite (γ-Fe2O3), and α-Fe2O3 during heavy oil combustion process. These enhanced performances in the heavy oil combustion by α-Fe2O3@OA could be favorable for improving the efficiency of the in situ combustion (ISC) technique in oilfields”. This conclusion was obtained on the basis of a joint analysis of the data of several experimental methods and techniques, such as porous medium thermo-effect cell (PMTEC) and thermogravimetry–infrared spectroscopy (TG–FTIR) experiments, scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDX), X-ray diffraction (XRD), and Mössbauer spectroscopy. Recently, Pranaba K. Nayak claimed that the choice of Mössbauer spectroscopy was excellent but the inability to extract a great deal of information from the carefully obtained Mössbauer spectra makes the study and its subsequent discussion of not much use. In this response, we reiterate that the phase identification in our previous paper by Mössbauer spectroscopy was carried out correctly and the phase components were determined with good statistical accuracy.

NH3-promoted heterogeneous reaction of SO2 to sulfate on α-Fe2O3 particles with coexistence of NO2 under different relative humidities

Heterogeneous reactions play an essential role in the research area of formation processes of secondary aerosols. In this study, heterogeneous reactions of NH3/SO2/NO2 with α-Fe2O3 particles at different relative humidities (RHs) were investigated by using a gas-flow system combined with diffuse reflectance infrared Fourier transform spectroscopy (DRIFTS). The results show that the presence of NH3 leads to the rapid conversion of SO2 to sulfate as a result of the proton transfer function and neutralization on the α-Fe2O3 particles in dry condition. NH3 can also promote the hydrolysis of NO2 dimers to HONO formation and result in the formation of more sulfate on the particle surface in humid conditions. On the other hand, water vapor plays both positive and negative roles in the uptake of SO2 during the reaction processes. When the RH increases from 0% to 62%, the formation rate of sulfate and uptake coefficient for SO2 in the initial stage increase about 3-fold. However, due to the inhibition effect of water layer between trace gases and active surface, the above values of reaction kinetic decrease about 21% when the RH increases from 62% to 72%. Our results may provide insight into the effects of NH3 and RH for the converting SO2 into sulfate on α-Fe2O3 particles, which supply basic data for the formation of secondary particles in field studies of atmospheric environment.

Recycled α-Fe2O3 nanoparticles adsorbents from Nd-Fe-B waste for methylene blue adsorption

Nanoparticles α-Fe2O3 were prepared using the waste liquid after recycling rare earths in Nd-Fe-B waste magnets. The most α-Fe2O3 particles have around 60-120nm diameters with the surface area of 144.51 m2 g -1 and pore size of around 5.0 nm. Methylene blue was used as a model pollutant to study the adsorption properties of the obtained α-Fe2O3 nanoparticles. The effects of contact time, pH value, loading mass of α-Fe2O3, and temperatures on the adsorption behavior were investigated. Results indicated that ultra-refined α-Fe2O3 particles can achieve an adsorption rate of 98% for the removal of methylene blue from waste liquids. Also, the removal of methylene blue by α-Fe2O3 particles presented an adsorption isotherm process which strongly fitted the pseudo-second-order kinetics model and Langmuir equation. The present work demonstrates a sustainable and efficient methodology for the re-use of Fe from magnet wastes and removal of MB, opening a promising and cost-effective avenue for the sewage-cleaning.

Forced hydrolysis of FeCl3 solutions in the presence of Cr3+ ions

Forced hydrolyses of FeCl3 solutions in the presence of Cr3+ ions without alkali addition were investigated at 160 and 200 °C. These precipitation systems were compared to corresponding reference systems. The isolated precipitates were characterized with XRD, 57Fe Mössbauer, FT-IR, FE SEM and photocatalytic measurements. Although chromium was not detected by EDS (Energy Dispersive X-ray Spectroscopy), the analysis of samples precipitated in the presence of Cr3+ ions showed several effects which can be attributed to the presence of these ions in the starting solutions. These effects are specifically well pronounced for samples obtained at 200 °C. For the highest concentration of Cr3+ ions and upon heating at 200 °C the transformation kinetics β-FeOOH to α-Fe2O3 was impeded. Relative intensities of prominent diffraction lines 104 and 110 of α-Fe2O3 changed as a result of the presence of Cr3+ ions. Changes in the size and formation of lemon-like particles instead of cube-like α-Fe2O3 particles were also noticed. The presence of Cr3+ ions in hydrolysing FeCl3 solution influenced the photocatalytic degradation of rhodamine B. Since no specific adsorption of Cr3+ ions occurred in the acidic pH medium, it was inferred that traces of Cr3+ ions enter into the structural tunnels of β-FeOOH crystals. The associates Cl−-Cr3+ are formed, which in the next step destabilize the crystal structure of β-FeOOH particles. Cr3+ ions leave the crystal structure upon dissolution of β-FeOOH. It can be assumed that α-Fe2O3 crystals start to grow on very fine and thin β-FeOOH crystallites which were not completely dissolved, but were previously affected by Cr3+ ions.

Rapid Microwave Method for Synthesis of Iron Oxide Particles under Specific Conditions

The advantages of microwave technology over conventionally conducted experiments are numerous. Some of them are reduction in reaction time, a higher degree of process control, repeatability, and work safety. Microwave synthesis routes require a complete description of the experimental details, instrumentation, and design program of a microwave oven used in the experiments. In this work, microwave-assisted hydrothermal synthesis of hematite (α-Fe2O3) particles from 0.1 M FeCl3 solution in highly alkaline media with heating in a microwave oven at continuous microwave emission of 800 W at 150 °C, 200 °C, and 250 °C for 20 min are presented. Also, the influence of the percentage of the addition of a cationic surfactant, cetyltrimethylammonium bromide (CTAB) on the composition, size, and shape of the final product was investigated. The samples precipitated at 150 °C formed a final product consisting of goethite (α-FeOOH) and hematite particles in contrast to the those precipitated at 200 °C and 250 °C where pure hematite phase was obtained. In these synthesis routes, the CTAB caused to slow down the rate of the goethite-to-hematite transformation process at temperatures at 200 °C but did not affect the transformation at 250 °C.

Solid-State Precursor Impregnation for Enhanced Capacitance in Hierarchical Flexible Poly(3,4-Ethylenedioxythiophene) Supercapacitors.

Increasing capacitance and energy density is a major challenge in developing supercapacitors for flexible portable electronics. A thick electrode with a high mass loading of active electronic material leads to high areal capacitance; however, the higher the loading, the higher the mechanical stiffness and ion diffusion resistance, thereby hampering development of flexible supercapacitors. Here, we show a chemical strategy that leads to a hierarchical electrode structure producing devices with both an exceedingly high areal capacitance and superior flexibility. We utilize α-Fe2O3 particles as an oxidant precursor for controlling oxidative radical polymerization of the conducting polymer poly(3,4-ethylenedioxythiophene) (PEDOT) from the vapor phase. Our approach impregnates carbon cloth with α-Fe2O3 particles prior to monomer vapor exposure, resulting in state-of-the-art flexible nanofibrillar PEDOT supercapacitors possessing high areal capacitance (2243 mF/cm2 for two-electrode vs 6210 mF/cm2 for three-electrode) and high areal energy density (412 μWh/cm2).

Deep convolutional neural network image processing method providing improved signal-to-noise ratios in electron holography

Abstract An image identification method was developed with the aid of a deep convolutional neural network (CNN) and applied to the analysis of inorganic particles using electron holography. Despite significant variation in the shapes of α-Fe2O3 particles that were observed by transmission electron microscopy, this CNN-based method could be used to identify isolated, spindle-shaped particles that were distinct from other particles that had undergone pairing and/or agglomeration. The averaging of images of these isolated particles provided a significant improvement in the phase analysis precision of the electron holography observations. This method is expected to be helpful in the analysis of weak electromagnetic fields generated by nanoparticles showing only small phase shifts.

Field-dependent Morin Transition and Temperature-Dependent Spin-flop in Synthetic Hematite Nanoparticles

Background: In nano-size α-Fe2O3 particles, the Morin transition temperature was reported to be suppressed. This suppression of the TM in nano-size α-Fe2O3 was suggested to be due to high internal strain and to the enhanced role of surface spins because of the enhanced surface to volume ratio. It was reported that for nanoparticles of diameters less than 20 nm, no Morin transition was observed and the antiferromagnetic phase disappears. In addition, annealing of samples was reported to result in both an increase of TM and a sharper transition which were attributed to the reduction in defects, crystal growth, or both. Objective: In this work, we investigated the role of applied magnetic field in TM, the extent of the Morin transition, thermal hysteresis, and the spin-flop field in synthetic α-Fe2O3 nanoparticles of diameter around 20 nm. Methods: Hematite nanoparticles were synthesized using the sol-gel method. Morphology and structural studies of the particles were done using TEM, and XRD, respectively. The XRD patterns confirm that the particles are hematite with a very small maghemite phase. The average size of the nanoparticles is estimated from both TEM images and XRD patterns to be around 20 nm. The magnetization versus temperature measurements were conducted upon heating from 5 K to 400 K and cooling down back to 5 K at several applied fields between 50 Oe and 500 Oe. Magnetization versus magnetic field measurements between -5 T and +5 T were conducted at several temperatures in the temperature range of 2-300 K. Results: We report three significant findings in these hematite nanoparticles. Firstly, we report the occurrence of Morin transition in hematite nanoparticles of such size. Secondly, we report the slight field dependence of Morin transition temperature. Thirdly, we report the strong temperature dependence of the spin-flop. Zero-field-cooled magnetization versus temperature measurements were conducted at several applied magnetic fields. Conclusion: From the magnetization versus temperature curves, Morin transition was observed to occur in all applied fields at Morin transition temperature, TM which is around 250 K with slight field dependence. From the magnetization versus magnetic field curves, spin-flop in the antiferromagnetic state was observed and found to be strongly temperature dependent. The results are discussed in terms of three components of the magnetic phase in our sample. These are the paramagnetic, soft ferromagnetic, and hard ferromagnetic components.

Size effect of hematite particles on the Cr(VI) reduction by Shewanella oneidensis MR-1

Microorganisms are commonly bonded to various soil minerals, which may influence the redox processes and bacterial metabolism. However, little is known about the impact of particle size of soil minerals on these redox processes in the subsurface environment. In this study, the Cr(VI) bioreduction by Shewanella oneidensis MR-1 (S. oneidensis) was investigated in the presence of various hematite (α-Fe2O3) particles with average diameters of 1.0 µm (hem-1 µm) and 80.0 nm (hem-80 nm) under different pH conditions. Fourier transformed infrared spectroscopy coupled with two-dimensional correlation spectroscopy (FTIR-2D-COS) analysis and isothermal titration calorimetry (ITC) were used to explore the interaction between S. oneidensis and hematite and monitor the bacterial metabolic activity, respectively. X-ray photoelectron spectroscopy (XPS) was used to elucidate the Cr(VI) removal mechanisms. Our results showed that 78% of chromate can be reduced to Cr(III) by S. oneidensis alone. Whereas, chromate reduction rates were 62% and 85% in the presence of hem-1 µm and hem-80 nm, respectively. The enhancement of Cr(VI) reduction by S. oneidensis-hem-80 nm complex may be due to the large surface area as well as the positive charge of hem-80 nm at neutral pH, which influences the physical contact between S. oneidensis and iron oxides. The microcalorimetric results showed that both hem-1 µm and hem-80 nm promoted the normal physiological functions of S. oneidensis. XPS confirmed the gradual FeCr2O4 formation and Fe(II) depletion during the Cr(VI) reduction process. This work expands our understanding of microbial-mineral interaction and its role in Cr(VI) removal mechanisms in the subsurface environment.

Flexible construction of RGO-encapsulated fine Pd/α-Fe2O3 composite with elevated Photo-Fenton reaction performance

A novel Pd/α-Fe2O3@RGO composite is prepared by modifying the fine α-Fe2O3 with Pd nanoparticles (NPs) and encapsulated in reduced graphene oxide (RGO), which has excellent Fenton performance and its efficiency can be further promoted with visible-light assistance (up to 41.8%). The joint modification of Pd NPs and RGO was employed to address the restriction of α-Fe2O3 in Photo-Fenton (Ph-F) reaction. Meanwhile, the massive H2O2 supplement can be avoided by Pd NPs catalyzing HCOOH and O2 to in-situ generate H2O2. The α-Fe2O3 particle size (60-80 nm) and graphene ratio fraction (GRF, 20 wt%) were also optimized that the Pd/Fe2O3-1@0.20GRF exhibits the best Ph-F performance (100%) for AR73 degradation (150 mg/L, 50 mL) within 60 min. The diffuse reflection spectra (DRS) results indicate the catalyst has the strongest light utilization capacity, and the effective carrier transport and remarkable effect on inhibition of electron-hole recombination were identified by photoluminescence (PL), photocurrent and electrochemical impedance spectroscopy (EIS). Furthermore, the encapsulation of Pd/α-Fe2O3 in RGO was approved to enhance photoresponse capacity and maintain good stability during the consecutive Ph-F reaction. This work provides an insight for the development of Fe-based catalyst with high Ph-F efficiency and long-term steadiness.

Harnessing the biomedical properties of ferromagnetic α-Fe2O3 NPs with a plausible formation mechanism

Pure hematite (α-Fe2O3) phase of iron oxide NPs was successfully achieved by an in situ pH and calcination-temperature dependent simple chemical precipitation process by using ferric chloride precursor and ammonium hydroxide precipitant. XRD, FTIR, and FE-SEM data confirmed 700 °C and a pH value of 11as the optimized calcination temperature and pH value for the crystalline synthesis of nano α-Fe2O3 particles, respectively. FE-SEM and HR-TEM revealed finely spherical morphologies with an average size of (20–30 nm) with agglomerations. The metal-oxide phase formation of synthesized NPs was identified via FTIR spectra. The specific surface area was calculated using BET N2 adsorption-desorption technique, which confirmed the mesoporous nature of α-Fe2O3 NPs with a surface area of 74.531 m2/g. The magnetization measurements revealed the weak ferromagnetic nature of α-Fe2O3 NPs at room temperature (RT). Haemocompatibility assays demonstrated that up to the concentration of 100 μg/mL synthesized particles are highly compatible with RBCs. Antibacterial assays confirmed potential bactericidal activity of α-Fe2O3 against gram-negative strains. The invitro MTT method was performed to check the cell viability in a concentration-dependent manner.

Retraction Note to: Synthesis and characterization of Ni-doped α-Fe2O3 nanoparticles through co-precipitation method with enhanced photocatalytic activities

In the present study, an attempt has been made for synthesis, characterization and photocatalytic application of pure and Ni-doped α-Fe2O3 (hematite) nanoparticles by chemical co-precipitation method. The synthesized products have been studied by Thermo Gravimetric Analysis (TGA), Differential Thermal Analysis (DTA), X-ray diffraction (XRD), Transmission Electron Microscopy (TEM), Scanning Electron Microscopy (SEM), Fourier Transform Infra-Red (FT-IR), Raman spectroscopy, Ultraviolet–Visible (UV–Vis) analysis and Vibrating Sample Magnetometer (VSM). The TGA showed three mass losses, whereas DTA resulted in three endothermic peaks. XRD measurements confirm that all the prepared nanocrystals consist only in nanocrystalline hematite phase. TEM and SEM show that the size of the nanoparticles decreases with Ni-doping. FTIR and Raman spectroscopies confirm the phase purity and the phonon modes of the synthesized nanoparticles. The UV–Vis absorption measurements confirm that the decrease of particle size is accompanied by a decrease in the band gap value from 2.02 eV for α-Fe2O3 down to 1.81 eV for 8 mol% Ni-doped α-Fe2O3. Furthermore, the magnetic properties demonstrated that all of the samples exhibited ferromagnetic behavior at room temperature. On the other part, the photocatalytic activity of Ni-doped α-Fe2O3 particles was studied using methylene blue (MB) as model organic pollutants. The 8 mol% Ni-doped α-Fe2O3 nanoparticles disclosed that the discoloration of MB reached 86% after irradiation of 140 min.

Study of prednisolone and rituximab in nephrotic syndrome based on novel nanomaterials

In the search for a more reasonable yet effective treatment method, this study explores the application of nanometer magnetic particles and prednisolone combined with rituximab in children with nephrotic syndrome (NS). According to the diagnostic criteria of children with hormone sensitivity and frequent recurrence of primary NS from the nephrology group of the Chinese Academy of Pediatrics, 40 children with NS diagnosed in our hospital from January 2018 to October 2019 were selected. Nanomagnetic α-Fe2O3 particles were prepared by chemical reaction synthesis. Before and after treatment, urine protein, oral hormone dosage, changes in peripheral blood CD19 + B lymphocyte levels, changes in plasma immunoglobulin levels, and patient general improvement were observed, along with the recurrence of renal disease after treatment. Immunoglobulin was measured by the immunoturbidimetric method, and the endpoint of the follow-up was the first relapse after administration. This study shows that the use of nanomagnetic particles and prednisolone in combination with rituximab in the treatment of pediatric NS has a significant effect, improving the renal function indicators of children and effectively controlling the condition of children while maintaining a higher level of safety.