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Analisis Efektivitas Penggunaan Video Pembelajaran Dalam Peningkatan Hasil Belajar Siswa Sekolah Dasar

Penelitian ini bertujuan untuk menganalisis keefektifitasan penggunaan video pembelajaran dalam peningkatan hasil belajar peserta didik di sekolah dasar. Metode yang digunakan dalam penelitian ini adalah studi literatur dengan melakukan peninjauan berbagai penelitian yang berkaitan dengan topik yang dibahas serta mengkaji penelitian-penelitian terdahulu yang mempunyai kaitan terhadap penggunaan video pembelajaran dengan hasil belajar peserta didik. Dalam pengumpulan data peneliti akan menggunakan studi literatur terkait efektivitas penggunaan video pembelajaran sebagai upaya pendidik dalam meningkatkan hasil belajar peserta didik. Pencarian sumber literatur yang berkaitan dengan topik penelitian menggunakan perpustakaan digital dan database online yang dilakukan oleh peneliti. Hasil dari analisis penelitian ini menunjukkan bahwa penggunaan video pembelajaran dapat meningkatkan motivasi belajar dan hasil belajar peserta didik. Berdasarkan analisis di atas, dapat disimpulkan bahwa penggunaan video pembelajaran efektif dalam peningkatan hasil belajar peserta didik di sekolah dasar. Penggunaan video dalam proses pembelajaran membuat peserta didik dapat memahami materi yang dipelajari dengan mudah dan dipahami melalui gambar, suara dan animasi yang disajikan, sehingga dapat meningkatkan motivasi belajar dan hasil belajar peserta didik.

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Valorization of whey for green synthesis of carbon dots and their potential applications

Purpose This paper aims to develop carbon dots using whey as a valuable resource and to create a sustainable and biocompatible nanomaterial with potential applications in a variety of fields owing to its unique optical properties and antimicrobial capabilities, which are frequently used as sensing agents for detecting specific molecules in food, environmental and biomedical applications. Versatility of carbon dots (CDs) allows the utilization of these dots for a wide range of applications in areas such as food safety, antibacterial properties, production of composite polymers for food packaging, treatment of different diseases and detection of food-borne pathogens. Owing to their high brightness, low toxicity and excellent biocompatibility, CDs have attracted significant interest in food safety. This is also a cutting-edge technology that bids new ideas for treating various diseases. Design/methodology/approach Literature review related to using whey as the carbon source for synthesis of CDs was collected and studied from different sources like Google Scholar, Research Gate, online journals available at library of Banaras Hindu University, Web of Science and Scopus. A database of more than 100 scientific sources from different sources was made as per the headings and sub headings of the paper. Findings Whey generated as a by-product from the cheese industry contained a good amount of carbon and nitrogen that can be used for the fabrication of CDs. CDs produced using whey exhibited great photostability, high sensitivity and outstanding biocompatibility and also showed that Fe3+ ions could be quickly, sensitively and extremely selectively detected in an aqueous solution of CDs, with a revealing limit of 0.409 µM in the linear range of 0–180 µM. CDs are a promising area of study to a key component of next-generation multifunctional nanomaterials, promoting creativity, sustainability and useful solutions across a variety of industries, including health care and energy. The susceptibility of S. typhimurium (Gram-negative) was found to be higher than that of L. monocytogenes (Gram-positive) bacteria with MIC and MBC of 500 and 1000 µL/mL, respectively. Originality/value Whey-derived CDs are an environmentally beneficial substitute for conventional additives and their biocompatibility guarantees that they adhere to food safety regulations. In light of the future, the green volarization of dairy waste for the synthesis of CDs is consistent with the increasing worldwide focus on environmental responsibility and sustainability.

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Phytochemical Profiles, Antimicrobial and Antioxidant Activity of Knautia integrifolia (L.) Bertol. subsp. integrifolia

The genus Knautia (L.) (Caprifoliaceae) is widely distributed in the Mediterranean region and is represented by 11 species of flora in Turkey. This study conducted a detailed phytochemical investigation of the methanol extract of the whole plant of K. integrifolia using a combination of LC-ESI-FT-MS and NMR analyses. According to the results of this analysis, 25 compounds were identified in the methanol extract of K. integrifolia. The extract is particularly rich in phenolic secondary metabolites, including phenolic acid derivatives, flavonoid glycosides, and flavones, along with the presence of triterpenoid compounds. Additionally, the total phenolic content of the K. integrifolia methanol extract was evaluated. Considering the pharmacological activities reported for Knautia species, the antioxidant potential of the methanol extract was assessed using the DPPH radical scavenging assay, resulting in a value of 77.5% when compared to the ascorbic acid standard. In this study, antimicrobial activity tests were performed on K. integrifolia methanol extract for the first time. The results indicated that the extract demonstrated greater susceptibility to Staphylococcus epidermidis compared to the control group. At the same time, Pseudomonas aeruginosa exhibited a minimum inhibitory concentration value, indicating high sensitivity to the methanol extract.

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The Japanese encephalitis virus NS1 protein concentrates ER membranes in a cytoskeleton-independent manner to facilitate viral replication.

Orthoflaviviruses remodel the endoplasmic reticulum (ER) network to construct replication organelles (ROs) for RNA replication. In this study, we demonstrate that the Japanese encephalitis virus (JEV) NS1 protein concentrates ER membranes in the perinuclear region, which provides a substantial membrane source for viral replication. Subsequently, the virus forms main replication organelles within this membrane-concentrated area to facilitate efficient replication. This process relies on the ER localization signal, glycosylation, dimerization, and membrane-binding sites of the NS1 protein. In conclusion, our study highlights the role of the NS1 protein in the formation of the ROs by JEV, providing new insights into orthoflavivirus replication.IMPORTANCEOrthoflaviviruses use the endoplasmic reticulum (ER) membranes for replication by forming invaginations to assemble the replication organelles. Here, we found that Japanese encephalitis virus (JEV) utilizes the NS1 protein to concentrate a significant number of ER membranes in the perinuclear area, thereby providing a membrane source for viral replication and facilitating the formation of main replication organelles (MROs). This process depends on the ER localization signals of NS1, as well as its glycosylation, dimerization, and membrane-binding sites, but not on the cytoskeleton. In summary, our study highlights how NS1 remodels ER membranes to facilitate the formation of MROs for JEV, thereby accelerating viral replication.

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