Abstract
A highly atom-economic, one-pot synthesis of functionalized piperidines is reported by a multi-component condensation reaction between β-keto ester, two equivalents of aromatic aldehyde, and two equivalents of amine in the presence of a catalytic amount of ZrCl4. The advantages of this protocol are good yields, short reaction time, mild reaction conditions, no need for column chromatography, more readily available, inexpensive catalyst, and simple work-up procedure.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
