Abstract
Bovine tuberculosis (BTB) is an important zoonotic disease that affects both domestic animals as well as humans in many countries of the world. The disease is caused by Mycobacterium bovis, which is responsible for 10–15% of human tuberculosis cases. BTB poses an occupational health hazard to the cattle owners, butchers, animal attendants, and veterinarians. The source of infection is exogenous and the respiratory tract is considered the chief portal of entry of the organism. The mode of spread of bacteria is aerogenous. BTB is endemic in Ethiopia, and it is mostly transmitted to people through the consumption of unpasteurized contaminated milk. Miliary tubercular lesions, chronic cough, blockages of the airways, alimentary system, or blood vessels, and lymph node enlargement are all symptoms of tuberculosis. Single intradermal or comparative intradermal tuberculin tests are useful delayed-type hypersensitivity tools for diagnosing tuberculosis in live animals. It is also employed in tuberculosis eradication programs and international trade activity. Vaccination of calves with an attenuated BTB strain known as Bacillus of Calmette and Guerin, as well as testing and culling, is significant measures in the prevention and control of BTB in endemic areas like Ethiopia. The proper pasteurization of milk before human consumption is a significant measure to reduce the public health risk posed by BTB.
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