Abstract
In this study, a mesoporous crystalline material including zinc metal–organic framework (Zn-mMOF) structure as a platform material synthesized by electrochemical method on glassy carbon electrode (GCE) and incorporated with copper ions by a simple chemical method, Cu/Zn-mMOF/GCE, was introduced for electrodetermination of the amoxicillin (AMOX). After physicochemical characterization of the modified electrode, it was used as an electrocatalyst toward oxidation of AMOX in 0.1 M NaOH solution. The Cu/Zn-mMOF/GCE showed high electrocatalytic activity for oxidation of AMOX with large catalytic rate constant; Kcat = 3.9 × 105 cm3 mol−1 s−1. The obtained results indicated that the incorporation of the Cu(II) ions plays an important role in the electrochemical and electrocatalytic activities of the Cu/Zn-mMOF/GCE for the oxidation of AMOX. The proposed modified electrode as a sensor exhibits excellent performances including a wide linear response range (1.0–205 µM), low detection limit (0.36 µM), high sensitivity (0.0256 µA µM−1 cm−2), high stability, short time response, and excellent reproducibility. The developed sensor was successfully applied for determination of AMOX in real samples.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
