Abstract
The three-component Hantzsch condensation of various aryl aldehydes, dimedone, and methyl 3-aminocrotonate was investigated in the presence of MCM-41-supported ZnNO3. The polyhydroquinoline products which were obtained under mild conditions and very easy workup were evaluated for anti-cancer activities against MCF-7, SK-BR-3, and HT-29 of breast and colon cancer cells. The fluorescence emission of some products was also studied and their optical parameters were reported.
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