Abstract
Zinc triflate-mediated nucleophilic addition of allytrimethylsilane, silyl enol ethers and terminal acetylenes to cyclic N-acyliminium ions at room temperature in CH 2 Cl 2 is described. The corresponding α-substituted heterocycles were obtained in moderate to good yields. The versatility of this reagent was demonstrated in the one-pot generation of the N-acyliminium ion and the zinc alkynylide species, followed by their coupling reaction to afford propargylic adducts in moderate yields.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.