Abstract
The stoichiometries and stability constants of proton and zinc(II) complexes of two phosphonic acid analogues of glutamic acid and three analogues of pyroglutamic acid (5-oxopyrrolidine-2-carboxylic acid) have been determined potentiometrically at 25 °C and at ionic strength 0.2 mol dm–3(KCl). Complementary studies by means of 31P and 13C NMR spectroscopy were also undertaken and indicated that the analogue obtained by the replacement of the γ-carboxylic group of glutamic acid by a phosphonic acid moiety and the phosphonic acid analogue of pyroglutamic acid exhibit predictable properties when complexing zinc(II) ions. The analogue obtained by the replacement of the α-carboxylic group by a phosphonic acid group underwent chemical transformation upon reaction with zinc(II) ions under neutral and alkaline conditions yielding most probably a cyclic phosphonamidate composed of two ligand molecules. The crystal structures of some analogues of pyroglutamic acid were also determined.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Journal of the Chemical Society, Dalton Transactions
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
