Zastosowanie pregabaliny u chorej z przewlekłym bólem neuropatycznym po zabiegu onkologicznym – opis przypadku

Abstract

Chronic postsurgical pain is a frequent iatrogenic complication and the consequence of surgical treatment of neoplastic disease. The risk of developing chronic postsurgical pain depends on the type of surgery, its extent, but also on the patients’ factors. Neuropathic pain may occur in 50% of patients with chronic postsurgical pain and can only be treated symptomatically, both with pharmacotherapy and non-pharmacological methods. The recommended drugs are antiepileptic drugs, antidepressants, opioid analgesics and topical drugs. These drugs have proven their effectiveness in the population of patients with neuropathic pain unrelated to cancer treatment, but there are still no high-quality studies assessing their effectiveness in patients with chronic postsurgical pain resulting from oncological surgery. Studies in small groups of patients available in the literature confirm the effectiveness of antiepileptic and antidepressant drugs in this group of patients, what is observed in clinical practice as well. The article presents a case of a patient with severe neuropathic pain in the course of chronic postsurgical pain who was successfully treated with pregabalin in combination with tramadol and paracetamol.