Abstract
Exposure to childhood trauma is a major risk factor for psychiatric disorders. Delineating the neurodevelopmental mechanisms linking early-life trauma to psychopathology is critical for the early identification of risk and optimizing interventions to promote resilience. Maltreatment-exposed youth show alterations in fear conditioning and related hippocampal-frontoamygdala circuitry, yet much remains unknown about extinction and extinction recall, which are central to discriminating threat from safety following trauma.
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