Abstract

Background: Coronary artery bypass grafting (CABG) is referred to as the gold standard therapeutic modality for treating coronary artery disease (CAD) among both old or young patients. hypertension, diabetes, Increased BMI and obesity, etc. are among the major risk factors for the development of cardiovascular diseases. The aim of the current study was to highlight the increasing rate of CAD and associated CABG surgery among young adults and to identify the potential risk factors associated with it.
 Methodology: In this hospital based observational study, CAD patients ≤40 years of age admitted to the cardiac surgery department of a leading cardiac center for CABG surgery were included in the study. The study continued from 5th January 2018 to 21st August 2019 and the data of 184 patients who underwent CABG was collected during this time period. The details regarding patients' age, weight, height and body mass index (BMI) were obtained at the time of initial examination. Moreover, medical records, familial history and risk profile were also monitored. The collected data was analyzed using SPSS Version 22.0.
 Results: A total of 184 CAD patients who underwent CABG surgery were included in the study and 114(62%) of them were males and 70(38%) were females. The age range was 25 to 40 years with the mean age of 36.5±3.17 years. The risk profile displayed that increased BMI was the major contributor for cardiovascular disease i.e. 38% patients were overweight, 10.9% were in Obese I category and 5.97% were in obese II category. Following obesity, hypertension (49.5%), diabetes (29.9%) and dysfunctional lipids (14.7%) were common comorbid conditions. While smoking and positive familial history also contributed to the risk ratio. It was observed that hypertension, diabetic history was more among overweight and obese individuals (p=0.029 & 0.666).
 Conclusion: Young CAD patients ≤40 years of age display decreased risk and adverse outcomes as compared to the older counterparts but the clinical pattern of presentation is different and hence require different strategic attention.

Highlights

  • coronary artery disease (CAD) has become one of the most prevalent cardiovascular diseases among the developing countries with highest reported mortality and morbidity[1]

  • Since the disease risk was scarce among the young people, the data and studies regarding the presence of CAD, its outcomes and the associated risk factors in this young age group hasn’t been explored in comparison to the older counterparts[3]

  • Cardiovascular diseases were known to affect to the older age group but recently the prevalence studies have shown a high frequency of CAD among younger adults

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Summary

Introduction

CAD has become one of the most prevalent cardiovascular diseases among the developing countries with highest reported mortality and morbidity[1]. Since the disease risk was scarce among the young people, the data and studies regarding the presence of CAD, its outcomes and the associated risk factors in this young age group hasn’t been explored in comparison to the older counterparts[3]. The aim of the current study was to highlight the increasing rate of CAD and associated CABG surgery among young adults and to identify the potential risk factors associated with it. The risk profile displayed that increased BMI was the major contributor for cardiovascular disease i.e. 38% patients were overweight, 10.9% were in Obese I category and 5.97% were in obese II category. Conclusion: Young CAD patients ≤40 years of age display decreased risk and adverse outcomes as compared to the older counterparts but the clinical pattern of presentation is different and require different strategic attention

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