Abstract
This Special Issue is a continuation of the first and second “Yeast Biotechnology” Special Issue series of the journal Fermentation (MDPI) [...]
Highlights
Issue series of the journal Fermentation (MDPI)
Yvanoff et al [1] developed a simple and affordable perfusion microfluidic chip containing a living yeast cell array composed of a population of green fluorescent protein (GFP)-tagged
A nanoscale approach to study the behavior of the pathogenic yeast C. albicans was develop by Kohler et al [2]
Summary
Living cell microarrays in microfluidic chips allow the non-invasive multiplexed molecular analysis of single cells. Yvanoff et al [1] developed a simple and affordable perfusion microfluidic chip containing a living yeast cell array composed of a population of green fluorescent protein (GFP)-tagged. Using atomic force microscopy (AFM)-based detection of the nanoscale motions of the yeast cells, it was demonstrated that strongly adhering strains reduce their nanomotion activity upon fibronectin exposure, whereas low adhering C. albicans remain unaffected. These results open novel avenues to explore cellular reactions upon exposure to stimulating agents and to monitor, in a rapid and simple manner, the adhesive properties of C. albicans
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