Abstract

Purpose: To present and review research highlights from recent literature published on the biology of osteoarthritis. Methods: A PubMed search was used to select articles published since the 2017 OARSI congress, with a research focus on the biology of osteoarthritis. Results: Highlighted articles and developing themes from the last year have been identified from the published literature. Emerging areas to be discussed include studies on the role of cell senescence in regeneration, the contribution of progenitor cells to skeletal repair, and the harnessing of the properties of articular cartilage itself in the therapeutic modulation of signalling pathways. Conclusions: Significant developments and their implications for further research and potential therapeutic progress are discussed.

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