Abstract
BEHAVIOUR can be stimulated as well as disrupted by cortical spreading depression (CSD)—the massive wave of neural depolarization and subsequent EEG depression which can be induced to spread slowly over a cortical hemisphere by injection of KCl. Eating, drinking and locomotor behaviour have been elicited in rats by administering single waves of CSD (ref. 1). Consummatory behaviour was most likely to be elicited if an animal had extensive feeding experience in the testing chamber. I wish to describe two further effects of single waves of CSD, the induction of penile erections and of stretching and yawning responses.
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