Abstract
Y chromosomal STRs show sufficient variability among individduals in a population and a high degree of geographical differentiation, such that their polymorphic character makes them especially suited for population genetic studies. To investígate the polymorphism of a set of 17 Y-STR loci in northern China, we genotyped the 17 Y chromosomal STR loci in a population sample of 377 unrelated males from eight ethnic populations in northern China. We calculated the haplotype frequencies, Rst value and carried out the analysis of molecular variance (AMOVA). We then drew the multidimensional scaling analysis (MDS) plot and phylogenetic tree based on the Rst value. All populations showed a high level of haplotype diversity, with low inter-population variance as measured by an analysis of molecular variance. However, the genetic distances were significant when the eight populations were compared to other populations. By MDS and the phylogenetic tree, we found that the eight populations had a close relationship and Xibo had a northeast origination.
Highlights
The Y chromosome is inherited from father to son and the majority of its DNA lacks recombination
analysis of molecular variance (AMOVA) of the eight ethnic populations in northern China indicated that 96.36% of the variation was found within populations, whereas only 3.64% was among populations (Table 3)
The results showed that the eight northern China populations and Shandong Han were in a clade, while the other populations were in another clade (Fig. 3)
Summary
The Y chromosome is inherited from father to son and the majority of its DNA lacks recombination. Y chromosomal STRs show sufficient variability among individuals in a population and a high degree of geographical differentiation (Jobling and Tyler-Smith 1995). Their polymorphic character makes them especially suited for forensic, genealogical and population genetic studies (de Knijff et al 1997; Gusmao et al 2006; Jobling et al 1997; Schultes et al 1999). The minimal haplotype, which consists of the loci DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393 and DYS385, can distinguish approximately 76.1-95.5% of male individuals in various populations (Kayser et al 2002; Roewer et al 2001; Schoske et al 2004). Despite the utility of the minimal haplotype, additional Y-STR loci are required to improve the ability to distinguish different paternal lineages. A set of 17 Y-STR loci had been analyzed in some populations and exhibited
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