Xây dựng ảnh não ba chiều sử dụng phương pháp quang cận hồng ngoại

Abstract

Functional near-infrared spectroscopy (fNIRS) is a non-invasive technique utilized to measure hemoglobin concentration of human brain signal. Temporal resolution of this method is high (aproximately 1 ms). However, its spatial resolution is limited (approximately 10 mm) compared with other non-invasive techniques. Therefore, in the present study, fNIRS based 32-optodes are utilized to measure human brain hemodynamic response of 5 male participants with arithmetic tasks. Coordinates of 256 voxels are computed based on the optode geometry. Coefficient of differential path-length factor in Beer-Lambert equation is estimated as a distance function to compute absorption coefficients. The mean concentration of Oxy- and deOxy-hemoglobin obtained from absorption coefficients is utilized to reconstruct 3-dimension brain imaging. The experimental results showed that the proposed method can detect the brain activity with higher spatial resolution than that using conventional approach.