X-ray microanalysis of dentine in primary teeth diagnosed Dentinogenesis Imperfecta type II

N Sabel,A Robertson,J G Norén,D H Cornell

doi:10.1007/s40368-018-0392-2

N Sabel, A Robertson + Show 2 more

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AimTo analyse the elemental composition of dentine in primary teeth from children diagnosed with Dentinogenesis Imperfecta type II (DI) and from normal sound primary teeth using X-ray microanalysis.Materials and methodsX-ray microanalysis of the elements C, O, Na, Mg, P, Cl, K and Ca were performed in the dentine of five normal primary teeth and in seven primary teeth diagnosed DI. The analysis was made in a low magnification in 10 points from the enamel-dentine junction/root surface toward the pulp. The data was also evaluated with an inductive analysis.ResultsLower values for C were found in DI-dentine compared with normal dentine. Na had significantly higher values in DI-dentine while Mg had significantly lower values. The inductive analysis revealed that Na and Mg were the most important elements for discriminating DI-dentine from normal dentine.ConclusionsDentine in primary teeth from patients diagnosed with Dentinogenesis Imperfecta type II analysed with XRMA have lower values of C and Mg and higher values of O and Na compared with normal primary dentine.

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Dentinogenesis Imperfecta (DI) is an inherited single-gene disorder affecting the dentine which is classified into two main groups, Dentinogenesis Imperfecta type II (DI) type I and DI type II (Shields et al 1973; Seow 2014)
Reports of elemental analyses of the dentine in Dentinogenesis Imperfecta are few (Kerebel et al 1981; Wieczorek and Loster 2012) and the aim of this study was to analyse the elemental composition of dentine in primary teeth from children with DI and from normal sound primary teeth using X-ray microanalysis (XRMA)
The present study has shown that the concentration profiles for C, O, Na and Mg measured by XRMA in dentine from primary teeth diagnosed with Dentinogenesis Imperfecta type II (DI) differ from normal primary dentine

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Introduction

Dentinogenesis Imperfecta (DI) is an inherited single-gene disorder affecting the dentine which is classified into two main groups, DI type I and DI type II (Shields et al 1973; Seow 2014). Simmer 2007; Barron et al 2008; Bailleul-Forestier et al 2008a, b). Teeth affected by DI type II have an opalescent appearance with a colour varying from greyish to brown with blue streaks and often enamel is chipped off at the enamel-dentine junction (Shields et al 1973; Levin et al 1983; McKnight et al 2008; Leal et al 2010). Since the enamel is normal regarding its structure and mineralisation the colour of the teeth is a result of the colour of the underlying dentine. In DI type II, X-ray radiographs reveal pulp chambers which progressively obliterate, resulting in a denser dentine structure enhancing the deviation of colour of the teeth. The defect dentine in DI type II has been attributed to the weakness in the attachment between enamel and dentine creating the problems of chipping off of the enamel at the enamel-dentine junction (Gallusi et al 2006; Wieczorek and Loster 2013)

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