Abstract
A number of plant natural products are of commercial interest for pharmacy, medicine, agriculture, or nutrition. A challenge for biotechnology is the production of such compounds in vitro. Whereas callus and suspension cultures of plants mostly fail as production systems, differentiated root cultures provide a better platform. We established normal and transformed root cultures of Ophiorrhiza mungos, which produce the anticancer drug camptothecin in yields, which are similar to differentiated plants.
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