Abstract
Due to the prevalence, the diversity of disease course, and the range of systems attacked by viral particles, COVID-19 pandemic turned out to be a challenging experience for both medical staff and patients all over the world. It is essential to remember that the infection affects health state and wellbeing of patients including their comorbidities and chronic conditions. The example of such wide-spread coexisting conditions is diabetes mellitus. In this paper, we evaluate the influence of SARS-CoV-2 infection and diabetes mellitus, especially considering the autoimmune diabetes mellitus type 1. The review describes possible pathomechanisms of glucose homeostasis disturbances in relation to the destruction of pancreas and other organs by viral particles. Moreover, the aim of the paper is to show a complex connection between therapeutic management of both COVID-19 and diabetes. We describe suggested consequences of glucocortycoids treatment and modifications in insulin therapy applied in diabetes mellitus type 1.
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