Abstract
The aim of this study was to investigate the wound healing activity of low frequency and high frequency TENS on excision wound model in rats.Excision wound:Thirty rats, Wistar, 250–300 g were anesthetized and an excisional wound was performed. The animals was treated with placebo ‐ TENS simulation (equipment off), low‐frequency TENS (2 Hz) and high‐frequency TENS (100 Hz) for 7 days. The residual wounds were analyzed and removed. Experimental protocols were approved by the animal care and use committee at Federal University of Sergipe (CEPA 69/2011). Serial histological sections were obtained and stained by histochemical techniques (Hematoxilin‐Eosin – HE and Sirius red) and immunohistochemical techniques. The results suggest that the high‐frequency TENS reduced (p < 0.05) wound areas. This evidence shows that high‐frequency TENS modulates the wound healing process.
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