Abstract
World Kidney Day 2016 focuses on kidney disease in childhood and the antecedents of adult kidney disease that can begin in earliest childhood. Chronic kidney disease (CKD) in childhood differs from that in adults, as the largest diagnostic group among children includes congenital anomalies and inherited disorders, with glomerulopathies and kidney disease in the setting of diabetes being relatively uncommon. In addition, many children with acute kidney injury will ultimately develop sequelae that may lead to hypertension and CKD in later childhood or in adult life. Children born early or who are small-for date newborns have relatively increased risk for the development of CKD later in life. Persons with a high-risk birth and early childhood history should be watched closely in order to help detect early signs of kidney disease in time to provide effective prevention or treatment. Successful therapy is feasible for advanced CKD in childhood; there is evidence that children fare better than adults, if they receive kidney replacement therapy including dialysis and transplantation, while only a minority of children may require this ultimate intervention Because there are disparities in access to care, effort is needed so that those children with kidney disease, wherever they live, may be treated effectively, irrespective of their geographic or economic circumstances. Our hope is that World Kidney Day will inform the general public, policy makers and caregivers about the needs and possibilities surrounding kidney disease in childhood.
Highlights
For in every adult there dwells the child that was, and in every child there lies the adult that will be
In 2016, World Kidney Day will be dedicated to kidney disease in childhood and the antecedents of adult kidney disease that can begin in earliest childhood
Children who endure acute kidney injury (AKI) from a wide variety of conditions may have long-term sequelae that can lead to chronic kidney disease (CKD) many years later.[1,2,3,4]
Summary
For in every adult there dwells the child that was, and in every child there lies the adult that will be. American Pediatric Renal Trials and Collaborative Studies (NAPRTCS),[6] the US Renal Data System (USRDS),[7] and the European Registry for Children on Renal Replacement Therapy[8] include data for pediatric renal replacement therapy (RRT), and some, for CKD Projects such as the ItalKid[9] and CKiD (CKD in Children)[10] studies, the Global Burden of Disease Study 2013, and registries that exist in many countries provide important information, and more is required.[11]. The outcome depends on the available resources Results from projects such as the AWARE (Assessment of Worldwide AKI, Renal Angina and Epidemiology) study, a 5-nation study of AKI in children, are awaited.[13] Single-center studies and meta-analyses indicate that both AKI and CKD in children account for a minority of CKD worldwide.[2,3] it is increasingly evident that kidney disease in adulthood often springs from a childhood legacy
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
