Abstract
Complete genome sequences of about 90 bacteria have been determined. These genome sequences include ones from closely related strains. By comparing the structure of genomes across these strains, we are able to obtain the association between genome structures and phenotype such as pathogenicity. However, to determine the whole genome sequence, it takes a large amount of time and cost and it also needs huge facilities. So it is very important to compare some genomes which sequences have not been determined and to detect the diversity of them rapidly at a lower cost. We have developed Whole Genome PCR Scanning [2] and the computer software. We also applied this method to comparing some strains of Escherichia coli.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call