Abstract
To assess the incidence of collateral findings detected on whole-body magnetic resonance (WB-MRI) scans performed on patients with lymphoma. 114 patients (65 male; median age 45.2years, range 15-86) with histologically confirmed lymphoma (47 Hodgkin, 67 Non-Hodgkin) underwent WB-MRI. The collateral findings were classified into three classes, according to their clinical significance, as follows: not or low significant (class 1), moderately or potentially significant (class 2), and significant (class 3). A Chi-square (χ (2)) test was performed to assess the statistical significance of differences in the incidence of collateral findings based on age (≤50 and >50years old), gender and histology (Hodgkin and Non-Hodgkin Lymphoma). Ninety-one of 114 patients (79.8%) had one or more incidental findings on WB-MRI. Collateral findings were more frequent in class 1 (43%); abnormalities found in 35 patients (30.7%) were considered potentially significant, whereas seven patients (6.1%) demonstrated significant collateral findings requiring immediate treatment or further diagnostic evaluation. Collateral findings were more frequent in subjects over 50years old compared to those of 50years old or younger; differences were statistical significant (χ (2)=8.42, p<0.05). There were not statistically significant differences related to gender (χ (2)=0.17, p>0.05) and histology (χ (2)=0.24, p>0.05). WB-MRI is an attractive procedure that allows to detect incidental abnormalities of organs not involved by disease offering the opportunity to obtain an early diagnosis of asymptomatic life-threatening diseases.
Published Version
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