Abstract
Cells regulate their internal environments, homeostatically maintaining molecular concentrations, and adjusting these in response to stimuli. They succeed despite the regulatory networks responsible being intrinsically noisy. Random fluctuations in molecule counts are inherent in biochemical signal processing, and the role of this noise is incompletely understood. In particular, how does evolution structure networks to tolerate such noise? From an engineering perspective, how can we design synthetic networks with low output noise?
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