Abstract
ObjectivesThe aim of this systematic review was to establish the adjuvant clinical effect of brushing with a dentifrice containing purported active ingredients as compared to a regular sodium fluoride dentifrice with respect to the inhibition of overnight dental plaque regrowth from studies with human participants.MethodsMEDLINE‐PubMed, EMBASE and Cochrane CENTRAL were searched, up to June 2019. The inclusion criteria were controlled clinical trials with participants aged ≥ 18 years in good general health. Studies were included that evaluated the effect of toothbrushing with a dentifrice on the inhibition of overnight dental plaque regrowth when an active ingredient was added to the dentifrice as compared to a common sodium fluoride product. Data were extracted from the eligible studies, the risk of bias was assessed, and a meta‐analysis was performed where feasible.ResultIndependent screening of 213 unique papers resulted in 10 eligible publications that provided 14 comparisons. Stannous fluoride and triclosan dentifrices were found as the active ingredients. The descriptive analysis indicated that all, but two comparisons demonstrated an additional effect on the active‐ingredient dentifrice. The meta‐analysis supported and strengthened these findings. It showed that when plaque was scored digitally, a DiffM was −3.15(95% CI [−4.61:‐1.69], P < .001, prediction interval [−5.07;‐1.24]). When plaque was scored clinically, the difference of means (DiffM) was −0.33(95% CI [−0.49:‐0.16], P < .001, prediction interval [−0.87; 0.21]).ConclusionThe results of this review demonstrate moderate‐quality evidence that brushing with an active‐ingredient dentifrice with stannous fluoride or triclosan does provide an added clinically relevant effect concerning plaque inhibition capabilities that surpass the effect of a regular sodium fluoride dentifrice.
Highlights
Routine toothbrushing is perhaps the single most important step for an individual to take in order to reduce plaque accumulation and to reduce the consequent risk of plaque-associated diseases, such as periodontitis and caries.[1]
In healthy adults (P), what is the effect of brushing with a dentifrice containing purported active ingredients to inhibit overnight plaque regrowth (I) compared to a regular sodium fluoride dentifrice (C) according the clinical indices of dental plaque (O) using an overnight plaque accumulation model (S)?
End scores did provide a significant difference of means in favour of the use of dentifrice with stannous fluoride or triclosan (DiffM −0.33; P < .001; 95% Confidence interval (CI): [−0.49; −0.16])
Summary
Routine toothbrushing is perhaps the single most important step for an individual to take in order to reduce plaque accumulation and to reduce the consequent risk of plaque-associated diseases, such as periodontitis and caries.[1]. Dentifrices can help with stain removal, breath freshening and provide a feeling of cleanliness.[2]. Fluoride-containing dentifrices play an essential role in caries prevention.[3,4]. A recent systematic review concluded that dentifrice does not provide an added effect for the mechanical removal of dental plaque. In terms of plaque removal, toothbrushing is at least as effective as toothbrushing with a dentifrice.[5]. In this respect, it seemed that the mechanical action provided by the toothbrush was the main factor in the plaque removal process.[6]. Chemicals could prevent bacterial attachment, stop bacterial division and plaque growth, or may even remove plaque.[8]
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
