Abstract
BackgroundPrevious studies indicate that psychosocial factors can impact COPD prevalence. However, research into this association has predominantly focused on negative factors such as depression. The aim of this study was to examine whether high subjective wellbeing is associated with a lower risk of developing COPD.MethodsThe sample consisted of 12,246 participants aged ≥50 years from the Survey of Health, Ageing and Retirement in Europe. We used Cox proportional hazards regression to examine the relationship between wellbeing (measured using the CASP-12) and incidence of COPD over a follow-up period of 9 years.ResultsThere was a significant association between wellbeing and COPD risk. In age-adjusted analyses, a standard deviation increase in CASP-12 score was associated with a reduced risk of COPD; hazard ratios (95% confidence intervals) for men and women were 0.67 (0.60–0.75) and 0.80 (0.73–0.87) respectively. After additional adjustment for demographic and health behaviour variables, this association remained significant for men but not for women: the fully-adjusted hazard ratios were 0.80 (0.70–0.91) and 0.91 (0.82–1.03) respectively.ConclusionsGreater wellbeing is associated with a reduced risk of COPD, particularly in men. Future research is needed to establish whether gender reliably moderates this association.
Highlights
Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide [1]
Previous studies indicate that psychosocial factors can impact COPD prevalence
There was a significant association between wellbeing and COPD risk
Summary
Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide [1]. Recent reports suggest that prevalence rates of COPD may have stabilised in some developed countries as a result of reduced smoking prevalence [1]. In addition to traditional risk factors, there is evidence that psychosocial factors impact on COPD prevalence. Current evidence for this association comes predominantly from studies into negative psychosocial factors such as depression or anxiety. A longitudinal study involving 14,682 men and women, found that major depression at baseline was associated with a significantly higher risk of developing COPD over a two year follow up period. Previous studies indicate that psychosocial factors can impact COPD prevalence Research into this association has predominantly focused on negative factors such as depression. The aim of this study was to examine whether high subjective wellbeing is associated with a lower risk of developing COPD.
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