Abstract
Respiratory failure from severe asthma is a potentially reversible, life-threatening condition. Since asthma involves bronchospasm and mucous plugging, it causes increased pressure difference between peak and plateau pressure. The increased pressure difference between the two can be due to ventilatory strategy of asthma itself which involves increased inspiratory flow rate and square flow pattern to increase expiratory time. It is important that clinicians managing such patients understand the use of mechanical ventilation since wrong interpretation may lead to inappropriate decision making during weaning.
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