Abstract
The analysis of iron-containing products made in Russia for veterinarian use against iron deficiency anaemia in fur farming was carried out. The absence of hydroxide-polymaltose iron complexes on the pharmaceutical market has been shown and their promise as the main components for oral preparations has been substantiated. In this context, the Collective of the Department of Physiology, Pharmacology and Toxicology, FSBEI HE MGAVMiB-MVA named after K.I. Skryabin, in collaboration with the research and production company A-BIO conducted research to develop and study the effect of pharmacologically active compounds based on a polymer (iron-hydroxide polymantose) complex for treatment and prevention of microelemetosis in the fur animals.
Highlights
Key factor, decreasing the growth and development of fur animals of various breeds, is the disbalance in metabolism of trace elements in the body, which leads to impaired hair state and hair quality [1, 2]
The mineral compounds of various trace elements used for oral administration, their chelate compounds have a number of disadvantages, in the form of high toxicity, and a small functional role of the ligand, which is only responsible for maintaining the water solubility and bioavailability of the target ion, since the ligand and ion assimilated by the body separately
The use of trace elements in this form does not exclude the antagonism between the trace elements
Summary
Key factor, decreasing the growth and development of fur animals of various breeds, is the disbalance in metabolism of trace elements in the body, which leads to impaired hair state and hair quality [1, 2]. Microelementosis (iron deficiency anemia, hypothyrosis, hypocobaltosis, hypocuprosis, etc.) in fur animals, as well as in other animal species, is a very prevalent non-infectious disease, which causes significant economic damage. Causes of iron deficiency anemia are similar [1, 3, 4]. The main factor that affects growth, development, reproductive ability, hair and pelt quality is feeding. Complete (balanced in nutrients and energy) feeds allow you to achieve genetic potential of animal in productivity, and it is the basis for prevention and treatment of metabolic disorders
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