Development and application of iron supplements, and principles of iron deficiency anemia therapy in fur farming

Abstract

A key factor in the non-infectious disease of iron deficiency anemia, which slows down the growth and development of fur farming species, is metabolic disturbance of iron in the body, which leads to deprivation of condition and quality of furs. It has been shown that the use of supplements of ferrous and ferric iron leads to damage not only to the structural elements of the gastrointestinal tract, but also to other systems and organs, which is due to the fact that in the absence of oxygen in the tissues, the reduction of iron from the ferric form to the ferrous form with further transfer electrons from ferrous iron to hydrogen peroxide causes the formation of a hydroxyl radical, which launches a program for self-destruction. Several factors are proposed to solve the problem, including usage of iron supplements for oral use in fur farming - industry where they are not used enough, and conduction of research on development and study of the effect of physiologically-pharmacologically active compounds based on a polymer (iron-hydroxide polymantose) on fur animals for treatment and prevention of microelemetosis. It is being solved by the collective of the Department of Physiology, Pharmacology and Toxicology of Moscow state Academy of Veterinary Medicine and Biotechnology by K.I. Scriabin in cooperation with research and production company LLC Firm "A-BIO" on the basis of an analysis of literary and patent sources, production technologies, pharmacological characteristics of ongoing research to develop and study the effect of physiologically and pharmacologically active compounds based on polymer (iron-hydroxide polymantose) on fur animals in the treatment and prevention of iron deficiency anemia.