Abstract

Advances in polymer science have led to the development of novel drug delivery systems. Some polymers are obtained from natural resources and then chemically modified for various applications, while others are chemically synthesized and used. A large number of natural and synthetic polymers are available. In the present paper, only water soluble polymers are described. They have been explained in two categories (1) synthetic and (2) natural. Drug polymer conjugates, block copolymers, hydrogels and other water soluble drug polymer complexes have also been explained. The general properties and applications of different water soluble polymers in the formulation of different dosage forms, novel delivery systems and biomedical applications will be discussed.

Highlights

  • Advances in polymer science have led to the development of novel delivery systems

  • This review describes water soluble polymers: their properties and applications in pharmaceutical and biomedical industries

  • Polyacrylamide, is a synthetic polymer derived from acrylamide monomer which was originally introduced for use as a support matrix for electrophoresis in 1959 [47]

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Summary

Introduction

Advances in polymer science have led to the development of novel delivery systems. Polymers were used as solubilisers, stabilizers and mechanical supports for sustained release of drugs. Over a period of time, the functionalities of polymers have changed. The polymers have been synthesized to suit specific needs or rather solve specific problems associated with development of drug delivery systems. There is need to understand the role of polymers. Water soluble polymers have a wide range of industrial applications like food, pharmaceuticals, paint, textiles, paper, constructions, adhesives, coatings, water treatment, etc. The water soluble polymers have been divided into two categories (1) Synthetic and (2) Natural. This review describes water soluble polymers: their properties and applications in pharmaceutical and biomedical industries

Synthetic Water Soluble Polymers
Polyacrylamides
Polyoxazoline
Polyphosphates
2.10. Polyphosphazenes
Xanthan Gum
Pectins
Chitosan Derivatives
Dextran
Carrageenan
Guar Gum
Cellulose Ethers
Sodium CMC
Albumin
3.10. Starch or Starch Based Derivatives
Conclusions
Limitations
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