Abstract
Water-dispersible iron oxide nanoparticles (NPs) consistently demonstrated a significant interest in the field of biomedical applications. Through this report, we present the synthesis of monodispersed magnetite NPs with an excellent water-dispersibility by employing a modified thermal decomposition method. Synthesized NPs were characterized by x-ray diffraction, transmission electron microscopy, x-ray photoelectron spectroscopy, vibrating sample magnetometry and cytotoxicity assay. From the results, it is evident that the NPs are highly crystalline, of spherical morphology with diameters of 20 ± 1 nm, superparamagnetic, and cytocompatible. Finally, we probed NPs as a T2-weighted contrast agent in magnetic resonance Imaging which resulted in relatively high r2 values. Therefore, the NPs could be effectively used as a potential candidate for various biological applications.
Published Version
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