Abstract
Background Wall shear stress (WSS) is the friction force that blood flow exerts on the vessel wall. It is thought to affect the function of endothelial cells and the development of atherosclerosis and aneurysms. A promising technique to measure blood flow is three-dimensional phase contrast MRI (3D PC-MRI). Due to limited spatial resolution and SNR, estimating WSS from time-resolved 3D PC-MRI is challenging. In this study, a recently in-house developed WSS algorithm is tested on 3D PC-MRI in an intracranial aneurysm phantom, measured with steady flow at different resolutions.
Highlights
Wall shear stress (WSS) is the friction force that blood flow exerts on the vessel wall
Wall shear stress vectors derived from 3D PC-MRI at increasing resolutions in an intracranial aneurysm phantom
A recently in-house developed WSS algorithm is tested on 3D PC-MRI in an intracranial aneurysm phantom, measured with steady flow at different resolutions
Summary
Wall shear stress (WSS) is the friction force that blood flow exerts on the vessel wall. It is thought to affect the function of endothelial cells and the development of atherosclerosis and aneurysms. A promising technique to measure blood flow is three-dimensional phase contrast MRI (3D PC-MRI). Due to limited spatial resolution and SNR, estimating WSS from time-resolved 3D PC-MRI is challenging. A recently in-house developed WSS algorithm is tested on 3D PC-MRI in an intracranial aneurysm phantom, measured with steady flow at different resolutions
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