Abstract
Lung transplant (LTx) candidates may have both high and low body-mass index (BMI). We investigated the effects of BMI in lung transplantation outcome and survival. Patients from our center (Feb-2012 to Jul-2019) were divided into 5 BMI groups: <18.5, <25, <30, <35, ≥35 kg/m2 using WHO's nutritional standards. Using Cox proportional hazard regression, we examined any differences between these groups in age, gender, race, length of stay (LOS), lung allocation score (LAS), single, and double LTx type. Kaplan-Meier curve showed survival outcomes between the groups compared by Log-rank test. Data were presented as Mean ± Standard deviation and p<0.05 was considered significant. Out of 609 LTx recipients, etiology was 63.1% IPF, 24.3% COPD, and 12.6% others. Furthermore, 28.2% of patients were either underweight or normal weight, 36.9% were overweight, and 34.7% were obese as measured by BMI. Demographically, the patient population was 66% male, mean age 64±9, race 78% white 15% black, and 7% others, median LOS (17 days) and mean LAS 49±19. Kaplan-Meier graph (figure 1) showed no significant differences in 1,3,5 year survival among all the BMI groups (p=0.57). There were also no significant differences among all the groups with regard to LOS (p=0.91) and LAS (p=0.42). Despite larger numbers of overweight patients, there was no evidence of negative effect in survival outcome after LTx. Additionally, LOS and LAS did not have any effect in survival among five groups of BMI. This outcome suggests lung transplantation could be expanded to a wider variety of BMI patients.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call