Waardenburg Syndrome Anesthetic Management: Two Cases Experiences

Abstract

This article presents the anesthetic management of two cases of Waardenburg syndrome (WS) in patients undergoing cochlear implantation. Mutations in genes that control the neural crest cell migration and division during the embryonic period are the hallmark of the hereditary disorder known as WS. White forelock, bright blue eyes, heterochromia from iris coloring deficiency, unusual facial deformities, and sensorineural deafness are the key phenotypic characteristics of WS. The anesthetic management of patients with WS poses challenges due to their multisystem abnormalities.