UTERINE SAROMAS Retrospective Studies on 7 Cases at the Hassan II University Hospital in Fez

Abstract

Introduction: Uterine sarcomas are rare tumors, representing less than 3% of malignant tumors of the female genital tract and between 3 and 7% of malignant tumors of the uterine body. They are a heterogeneous group of tumors comprising different histological subtypes, but with a generally identical evolutionary profile. Unlike uterine epithelial tumors, and apart from low-grade endometrial stromal sarcomas, uterine sarcomas have a poor prognosis. They have a high rate of recurrence (between 50 and 70%), local and especially metastatic (in approximately 70% of cases). The objective of our work is to specify the epidemiological characteristics of uterine sarcomas, the diagnostic difficulties faced by practitioners at the clinical, radiological and anatomopathological stages, the modalities of management as well as the different determinants of the prognosis of these rare tumors. Patients And Methods: Seven cases of uterine sarcomas treated in the gynecology - obstetrics II department at the Hassan II University Hospital in Fez between 2019 and 2023 were analyzed retrospectively. Results: The average age of our patients varies between 50 and 75 years with an average of 62.2 years. Of the 7 patients, 90% are multiparous, 100% menopausal. 78% of our patients consulted for metrorrhagia. On the paraclinical level, we performed a pelvic ultrasound for all patients, 80% of the results of which were in favor of an enlarged uterus with a heterogeneous echogenic intracavitary image, hysteroscopy in 04 patients for exploration of postmenopausal metrorrhagia and magnetic resonance imaging in 06 patients. The diagnosis was made at the preoperative stage in five patients. 71% of our patients benefited from surgical treatment. The anatomopathological analysis of the surgical specimens showed that 05, 07 patients benefited from adjuvant radiotherapy, while a combined chemotherapy/radiotherapy postoperatively was indicated in 02 patients. One patient presented a recurrence having ...