Abstract
Background: Vulvar dermatoses are inflammatory disorders of genital skin causing itch, burning, and plaques with overlying excoriation and linear fissures. Objective: To assess the effectiveness of a soft foam based on Tiab® system (TF), complex of titanium micro crystals covalently bound with silver ions associated with hyaluronic acid, in the supportive treatment of lichen sclerosus (LS) and lichen simplex chronicus (LSC), the two common vulvar dermatoses. Method: 20 patients with the diagnosis of LS or LSC received an 4-week treatment, during which the subjects applied Mometasone furoate in the form 0.1% cream were treated with Mometasone furoate 0.1% cream in combination with TF once a day. Clinical symptoms (itching and burning) and signs (vulvar suface disruption) were documented at baseline and at the end of the four-week treatment. Results: There was a significant reduction of symptoms between the basal scores and the symptoms complaints at 4-week treatment. Moreover, a significant reduction of excoriations and linear fissures was observed. Conclusion: The present study shows that daily application of TF can be an effective adjunct for the treatment of vulvar dermatosis. The foam had not only a moisturizer action, it may also be associated with a reduction in epithelial disruption in the form of excoriations and fissures.
Highlights
Vulvar dermatoses are inflammatory conditions responsible for chronic or recurrent itching and burning
All of the patients received an 4-week treatment, during which the subjects applied Mometasone furoate in the form 0.1% cream on the affected vulvar surfaces, in combination with a soft foam based on Tiab® system (TF), complex of titanium micro crystals covalently bound with silver ions associated with hyaluronic acid used once a day
In terms of the subjective outcome, as reported by the patients there was a significant reduction of symptoms between the basal scores and the symptoms complaints at 4-week treatment (Figure 1)
Summary
Vulvar dermatoses are inflammatory conditions responsible for chronic or recurrent itching and burning. Vicariotto sclerosus (LS) and lichen simplex chronicus (LSC) are two of the most common vulvar dermatosis [1]. Vulvar dermatoses are inflammatory disorders of genital skin causing itch, burning, and plaques with overlying excoriation and linear fissures. Objective: To assess the effectiveness of a soft foam based on Tiab® system (TF), complex of titanium micro crystals covalently bound with silver ions associated with hyaluronic acid, in the supportive treatment of lichen sclerosus (LS) and lichen simplex chronicus (LSC), the two common vulvar dermatoses. Clinical symptoms (itching and burning) and signs (vulvar suface disruption) were documented at baseline and at the end of the four-week treatment. The foam had a moisturizer action, it may be associated with a reduction in epithelial disruption in the form of excoriations and fissures
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