Abstract
Background: Vulvar dermatoses are inflammatory disorders of genital skin causing itch, pain, dysuria and dyspareunia. Objective: To compare the efficacy of two intimate cleansers as adjuvants in the treatment of the two common vulvar dermatoses: Lichen sclerosus (LS) and lichen simplex chronicus (LSC). Method: 32 patients with the diagnosis of LS or LSC initially treated with Mometasone furoate 0.1% cream were then randomly assigned to receive either cleanser A (cleaner based on amigdalus dulcis, malva, jojoba oil, PCL solid, Hyaluronic acid) or cleanser B (cleaner based on Cocoyl Wtheat Amino Acids, Maltodextrins, Aveena sativa, Caprylic Glycol) twice a day in association with lanolin cream one application daily for 30 days, following which the lanolin cream was applied only when needed as a rescue treatment. The amount of the rescue cream used, rubbing, applicability and pleasantness of the product were classified before and after 60 days of treatment. Results: The differences between the two treatments for rubbing, applicability and pleasantness of the product were statistically non-significant, while “as needed” use of the emollient lanolin cream was significantly superior in a total number of doses in the B group versus the A group (8.25 vs 5.28 (P
Highlights
Vulvar dermatoses are inflammatory muco-cutaneous disorder of genital skin that form a frequent finding in the specialized center for vulvar diseases
The treatment was intensive during the first month. It consisted of the use of 1/2 fingertip unit (FTU), i.e. the amount of topical Mometasone furoate that is squeezed out from a standard tube on the fingertip of an adult once a day for four weeks, twice a week for four more weeks and subsequently topical steroid was applied only when needed as a rescue treatment
We divided the patients in two Groups according to the randomization list: Group A: the patients were prescribed to use the cleanser A twice a day in association with one application of lanolin cream daily for 30 days, following which the lanolin cream was applied only when needed as a rescue treatment
Summary
Vulvar dermatoses are inflammatory muco-cutaneous disorder of genital skin that form a frequent finding in the specialized center for vulvar diseases. They are debilitating diseases that cause itching, pain, dysuria, dyspareunia, and significant sexual dysfunction in women. Vulvar dermatoses are inflammatory disorders of genital skin causing itch, pain, dysuria and dyspareunia. Objective: To compare the efficacy of two intimate cleansers as adjuvants in the treatment of the two common vulvar dermatoses: Lichen sclerosus (LS) and lichen simplex chronicus (LSC). The best results of the cleaner A can be attributed to to the pool of moisturizing and emollient active ingredients but that of the soothing effects as well This shows that the role of intimate cleanser is for vulval cleansing, but can play a therapeutic role of moisturization and emollience
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