Abstract
The volatiles emitted by the ascomycetes Hypoxylon griseobrunneum and Hypoxylon macrocarpum (Hypoxylaceae, Xylariales) were collected by use of a closed-loop stripping apparatus (CLSA) and analysed by GC–MS. The main compound class of both species were polysubstituted benzene derivatives. Their structures could only be unambiguously determined by comparison to all isomers with different substitution patterns. The substitution pattern of the main compound from H. griseobrunneum, the new natural product 2,4,5-trimethylanisole, was explainable by a polyketide biosynthesis mechanism that was supported by a feeding experiment with (methyl-2H3)methionine.
Highlights
Fungi release a large number of different volatiles that belong to all kinds of natural product classes [1]
In continuation of this work, here we present the volatiles emitted by Hypoxylon griseobrunneum MUCL 53754 and Hypoxylon macrocarpum STMA 130423
The volatiles released by agar plate cultures of H. griseobrunneum and H. macrocarpum were collected using a closed-loop stripping apparatus (CLSA) [13]
Summary
Fungi release a large number of different volatiles that belong to all kinds of natural product classes [1]. The substitution pattern of the main compound from H. griseobrunneum, the new natural product 2,4,5-trimethylanisole, was explainable by a polyketide biosynthesis mechanism that was supported by a feeding experiment with (methyl-2H3)methionine.
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