VITILIGO TREATMENT WITH MANIPULATED FORMULATION CONTAINING TOPICAL ANTI-INFLAMMATORY DRUGS: CASE REPORT

Abstract

Introduction: Vitiligo is a dermatological condition that causes white patches on the skin due to the loss of melanocytes. Classified as an autoimmune disease, it is associated with genetic, environmental factors and oxidative stress. It occurs predominantly in people aged between 10 and 30 years, affecting the self-esteem and quality of life of patients. Objective: This study aimed to monitor a patient using a compounded formulation containing topical anti-inflammatories, regarding improvement in the pigmentation of the spots. Case Report: The volunteer presented vitiligo spots in the eye and eyelid region, leading to self-esteem problems because they are quite visible spots. The formulation containing topical anti-inflammatories was compounded in a Compounding Pharmacy in the city of Maringá (PR) and given to the volunteer, with instructions for use to apply once a day directly on the spots, always at night, after cleaning the affected area. The monitoring was carried out by the students weekly, through photos and application of a questionnaire to the volunteer. The treatment was carried out for 30 days, without any complications, discomfort or skin irritation. The patient reported having undergone the treatment without interruption, and after the total treatment time, there was a significant improvement in pigmentation. In the questionnaire applied, the volunteer reported that there was an improvement in the appearance of the spots, and the result can be seen in the weekly photos. This research was approved by the Ethics Committee for Research involving Human Beings of Uningá (CEP/Uningá), under protocol number 6,950,683.