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https://doi.org/10.1016/0014-5793(84)81296-x
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Cite Journal: FEBS Letters |  Publication Date: Nov 19, 1984 |
 Citations: 15 |
Affiliation: University of Paris-Sud, Université Paris Cité
The peptide Boc-4-methylene Glu-Glu-Val has been synthesized and shown to be a strong inhibitor of the vitamin K-dependent carboxylation catalyzed by a detergent solubilized rat liver microsome preparation. The inhibition is apparently competitive with respect to the substrate peptide and non-competitive with respect to HCO3-.
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