Abstract

Vitamin D and Zinc (Zn) play a crucial role in human biochemistry. Over the last decade, there has been a better understanding on the significant role of vitamin D and zinc in ear, nose, and throat disorders. They are responsible for regulating mucosal immunity. Although vitamin D recognized as a key micronutrient, there is a pervasive vitamin D deficiency globally. Zinc as a critical trace element in human metabolism, facilitates the antioxidant activity and toxin excretion, plays a vital role in hearing system, acts as a cofactor in many enzymes. Zinc tasks in diseases related to mucosal defense, control of seasonal allergic rhinitis and healing of scar tissues. Zinc is an abundant intracellular trace element. Even though a mild zinc deficiency can manifest with serious clinical pictures like impaired immune defense.

Highlights

  • Otology and vitamin DIt has long been attested that vitamin D, in tandem with calcium, is effective in bone mineralization and linked with bone disease

  • Recent studies revealed the connection of vitamin D, which is a key actor as immuno-modulator, with otologic disorders

  • Numerous predisposing factors have been suggested in the formation of disease induced by otitis media with effusion

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Summary

Introduction

It has long been attested that vitamin D, in tandem with calcium, is effective in bone mineralization and linked with bone disease. Numerous predisposing factors have been suggested in the formation of disease induced by otitis media with effusion. The relationship between otitis media with effusion and vitamin D deficiency has been reported [1]. This link can be attributed to an increased risk for allergic disorders in vitamin D deficiency or disordering effect of tuba eustachian in drainage system. With a disorder in tuba eustachian functioning, there is a risk of post-otitis media retraction pocket unless a protocol is followed to address underlying cause

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