Abstract
COVID-19 has errupted not only as a pandemic but as challenge to mankind. Life has come to a stand still. All spheres of life are affected not only in terms of jobs and economy but importantly health and well being. In Indian scenario this is of particular significance as autumn coincides with festivities, wedding season and mass gatherings. Outbreaks of respiratory viral infections, such as those caused by influenza A and Respiratory Synctial Virus have long been associated with changing season reaching a peak in winter season and nadir in summer months. Various factors could be attributed to this pattern like increased virus survival at low temperature, tendency of close gatherings in winter months and cold dry air reducing mucus in nasal passages. Clinically Vitamin D deficiency has been shown to associate with increased risk of diverse acute respiratory tract infections. It has been proposed that vitamin D, diminishes production of respiratory cytokines, which appear to play a central part in pathogenesis of severe COVID-19.
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