Vitamin C supplementation as an adjunct to nonsurgical therapy in the treatment of chronic periodontitis: A clinical and biochemical study

Abstract

Aim: The aim of the present study is to assess the effectiveness of Vitamin C supplementation, a known antioxidant, on periodontal health in patients with chronic periodontitis (CP) and salivary total antioxidant capacity (TAOC) levels. Materials and Methods: A sample of 50 patients diagnosed with CP and 50 healthy controls were selected for the present study. Fifty CP patients were further randomly divided into two groups. CP1 (25 patients received nonsurgical therapy alone) and CP2 (25 patients received Vitamin C supplementation (1500 mg/day) as an adjunct to nonsurgical therapy). Clinical parameters such as plaque index (PI) gingival index (GI), gingival bleeding index (GBI), pocket depth (PD), and clinical attachment level (CAL) were recorded at 1-month and 2-month post therapy. Salivary TAOC levels were measured by Koracevic's method at baseline and 2 months' post therapy. Results: Patients with CP showed lower salivary TAOC compared to control group (P