The total oxidant status and total antioxidant capacity of saliva in patients with chronic periodontitis before and after non – surgical periodontal treatment

Abstract

Objective: The aim of this study was to measure the total oxidant status (TOS) and total antioxidant capacity (TAOC) levels in the saliva of patients with chronic periodontitis, before and after non – surgical periodontal treatment (NSPT). In addition, we aimed to investigate the correlation between salivary TOS, TAOC levels and periodontal parameters. Materials and Method: This longitudinal study included 12 patients diagnosed with chronic periodontitis. The periodontal parameters (PlI, GI, PPD, CAL, BOP) and unstimulated saliva of the patients were evaluated at baseline and eight weeks after NSPT. The salivary TAOC and TOS levels were measured using assay kits according to the manufacturer's instructions. Results: At eight weeks after NSPT, the saliva TOS levels were lower and the saliva TAOC levels were higher significantly, compared to those at baseline (p <0.05). A correlation between TAOC and PPD at eight weeks after NSPT was found (p <0.05). Conclusion: The periodontal parameters and oxidative stress biomarkers improved after NSPT when compared to baseline. However, more studies are in need to confirm the correlation between oxidative stress biomarkers and periodontal parameters.