Abstract
The efficient synthesis of tetrahydro-2,6-dioxopyrimidin-4-yl)-2,3-dihydrophthalazine-1,4-dione derivatives via four-component reaction of hydrazine hydrate, phthalic anhydride, aromatic aldehydes and barbituric acid using vitamin B1 supported on alumina (VB1-Al2O3) as a heterogeneous catalyst under thermal solvent-free conditions in excellent yields is described.
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