Abstract
Knowledge of the limiting photo-thermal energy deposition in cells is of primary importance for new diagnostic applications of near infrared lasers. The influence of high-energy near infrared (NIR)-optical parametric oscillator (OPO)-irradiation on the MeWo melanoma cell line was investigated for different periods of illumination. Minor decreases of cell viability of 10% and 13% after 1 min and 5 min, respectively, were observed. After 15 min OPO irradiance the cell viability was reduced significantly. The results of CellTiter-Blue® viability assay were confirmed with a new lab-on-a-chip technology.
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