Abstract
To study prognostic factors for visual acuity (VA) after intravitreal bevacizumab injection (IVB) for macular edema (ME) associated with retinal vein occlusion (RVO), by evaluating the correlation between the final VA and VA at baseline and at 1, 3, and 6 months after the initial IVB. We studied retrospectively 79 eyes of 79 patients with ME secondary to RVO treated with IVB. The correlation between the final VA and VA at each visit was studied by using Pearson's correlation coefficient. Baseline VA was significantly correlated with the final VA (r = 0.552, P < 0.0001). Postoperative VA at 1, 3, and 6 months after the initial IVB, however, was even more closely correlated with the final VA (r = 0.793, 0.816, 0.893, respectively; P < 0.0001 in each case). Additionally, eyes with a VA of 20/40 or better at 1 month achieved a significantly better final VA than did eyes with a VA worse than 20/40 at 1 month (P < 0.0001). This tendency was seen also in each RVO subgroup. Although the baseline VA was significantly correlated with the final VA, postoperative VA was correlated even more closely with the final VA. VA shortly after the initial IVB seemed to reliably predict final visual outcome.
Published Version
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