Abstract

BackgroundTo assess the change in vision-related quality of life and psychosocial well-being of the patients with episcleritis and scleritis patients before and after treatment.ResultsThis one-and-a-half-year prospective study was conducted among 76 eyes of 71 new patients of episcleritis and scleritis. A structured questionnaire was used to assess the visual and to analyze the change in effect size. The male-to-female ratio was 1:1.536. Episcleritis was seen in 41 cases (57.7%) while scleritis was seen in 30 cases (42.3%). Patients with episcleritis had statistically significant improvement in general function score (GF) (p < 0.05) using paired t-test. The effect size showed medium improvement (approximately 0.5). Whereas there was no statistically significant change in psychosocial impact (PI), visual symptoms (VS) scoring, and a total score (p < 0.05) using paired t-test. The effect size showed no improvement for PI and total score and small improvement for VS score. Patients with scleritis had statistically significant improvement in general function score (GF), visual symptoms (VS) scoring and total score (p < 0.05) using paired-t-test. The effect size showed medium improvement (approximately 0.5) for general function score (GF) and total score. However, the effect size showed only a small improvement (approximately 0.2) for psychosocial impact (PI) score.ConclusionsVisionRelated Quality of Life of patients with scleritis showed significant improvement following treatment unlike episcleritis indicating scleritis more adversely affecting psychosocial well-being.

Highlights

  • To assess the change in vision-related quality of life and psychosocial well-being of the patients with episcleritis and scleritis patients before and after treatment

  • Unilateral involvement was seen in 38 patients (92.7%) with episcleritis and 28 patients (93.3%) with scleritis

  • The effect size showed no improvement for psychosocial impact (PI) and total score and small improvement for visual symptoms (VS) score (Table 1)

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Summary

Introduction

To assess the change in vision-related quality of life and psychosocial well-being of the patients with episcleritis and scleritis patients before and after treatment. Episcleritis is a mild, non-vision-threatening inflammation of the episclera that may recur over irregular intervals for many years. It is highly essential to recognize its benign nature and not to induce vision-threatening complications, by over treating episodes of episcleritis like steroid induced cataract and glaucoma. Scleritis causes vision loss via its complications or treatment-related complications due to its chronicity and Tamrakar et al Journal of Ophthalmic Inflammation and Infection (2021) 11:34 frequent relapses. The anterior segment complications of anterior scleritis include keratitis, uveitis, cataract, glaucoma, and cystoid macular oedema may develop in patients with uveitis associated with anterior scleritis. Posterior scleritis is associated with more visionthreatening complications like serous retinal detachment, optic disc oedema, choroidal effusion, macular oedema, and retinal vasculitis [1]

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